Results 171 to 180 of about 709,620 (295)

Research with black and minority ethnic people using social care services

open access: yes, 2012
This review addresses research methods with Black and Minority Ethnic (BME) peoplen using adult social care and support in England. During the last decade there have beenconsiderable changes in how ethnicity is understood.
Vickers, Tom   +5 more
core  

Lactate‐Driven Restriction of Mitochondrial Permeability Transition Promotes Resistance to Chemo‐Immunotherapy by Suppressing Tumor PANoptosis

open access: yesAdvanced Science, EarlyView.
Tumor‐derived lactate establishes a metabolic lock that drives chemo‐immunotherapy resistance by suppressing PANoptosis. Mechanistically, KAT8 lactylates the mitochondrial translocator ANT2, which recruits PGAM5 to dephosphorylate CypD. This cascade restricts mitochondrial permeability transition pore opening, preventing pro‐inflammatory mtDNA leakage.
Sen Zhong   +20 more
wiley   +1 more source

Gene Correction Enhances Dopaminergic Cell Therapy in a Nonhuman Primate Model of Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan   +29 more
wiley   +1 more source

Uterine fibroids and Black people of African descent globally: a scoping review protocol. [PDF]

open access: yesBMJ Open
Jefferies K   +9 more
europepmc   +1 more source

William Black and Others

open access: yes
5 x 4 glass plate, three people sitting on the steps of an elevated covered porch with a man standing near the house entrance at the top of the stairs, one man has an arm in a sling284 H86-038 Lester Black Collection Vault 211-313 Box 3 of 8 Glass plates
Black, Lester
core  

Biomimetic Nanoplatform for Dual Target Nano‐Metabolic Therapy in Diabetes‐Associated Biofilm Infections

open access: yesAdvanced Science, EarlyView.
A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li   +13 more
wiley   +1 more source

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