Results 61 to 70 of about 449,109 (307)

Straight Gods, White Devils: Exploring Paths to Non-Religion in the Lives of Black LGBTQ People

Secularism and Nonreligion, 2017
To examine paths to non-religion in the lives of black LGBTQ people, I analyze 10 interviews of black LGBTQ people who were raised Christian. Utilizing an intersectional lens, I conclude that lessons of the Christian home, reinforced in religious school ...
Simone Kolysh
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

In the footsteps of Einstein, Sagan and Barnard: Identifying South Africa’s most visible scientists

South African Journal of Science, 2017
Highly visible scientists are increasingly recognised as influential leaders with a special role to play in making science part of mainstream society. Through consultation with a panel of 45 experts working at the science–media interface, we sought to ...
Marina Joubert, Lars Guenther
doaj   +1 more source

There is nothing honourable about honour killings: gender, violence and the limits of multiculturalism [PDF]

, 2007
'Honour killings' are extreme acts of domestic violence culminating in the murder of a woman by her family or community. However only in relation to religious and ethnic communities is the concept of 'honour' invoked as motivation for domestic violence ...
Meetoo, Veena, Mirza, Heidi
core   +3 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Discrimination in the Private Sphere. A subjective Right or a Legal Abuse. An European North American Legal Comparative Study [PDF]

, 2016
En el presente trabajo se estudian los límites de la autonomía privada desde la perspectiva del derecho a la igualdad y del principio de no discriminación tanto en el derecho norteamericano como en el europeo, con especial incidencia a la doctrina ...
De-Torres-Perea, Jose Manuel
core  

Including the religious viewpoints and experiences of Muslim students in an environment that is both plural and secular [PDF]

, 2010
This paper sets out the context and some main lines of argument about the education of Muslim children in England, including concern over low attainment, over segregation and violent extremism.
A Siddiqui, Association of Muslim Social Scientists, C Byfield, C Evans, D Hodson, DCSF, Department for Children, Schools and Families Publications, Department for Education and Skills, DfES, DfES, G Sarwar, Home Office, Home Office, J Habermas, J Ipgrave, J Miller, JM Halstead, Julia Ipgrave, K Haw, K Khan, L Archer, M Mirza, M Parker-Jenkins, MI Coles, MI Coles, Muslim Council of Britain, Office for Standards in Education, Children’s Services and Skills (Ofsted), P Lewis, R Barker, R Jackson, R Richardson, Runnymede Trust, S Akhtar, S May, T Abbas, U Maylor   +35 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Learning and Living Difference That Makes A Difference: Postmodern Theory & Multicultural Education [PDF]

, 2002
The application of postmodern theory to a transformative understanding of multiculturalism can make a difference. Multicentered culture, antiessentialist race consciousness, and political equity—aspects of a transformative multiculturalism put forward in
Jacobs, Walter R
core   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source