Results 141 to 150 of about 2,505 (255)

Phosphorescent Iridium Hydrazinonicotinic Acid (HYNIC) Complexes That Bind to Prostate Specific Membrane Antigen: Potential Photodynamic Therapy of Prostate Cancer

Chemistry – A European Journal, EarlyView.
A phosphorescent iridium(III) complex has been prepared with a 6‐hydrazinonicotinic acid (HYNIC) ligand tethered to a lysine‐ureido‐glutamatic acid pharmacophore, which binds to an enzyme, called prostate‐specific membrane antigen (PSMA), which is overexpressed in prostate cancer.
La'El Kimchi, Emily R. McGowan, Katherine A. Morgan, Jonathan M. White, Trevor A. Smith, Stacey E. Rudd, Paul S. Donnelly   +6 more
wiley   +1 more source

Assessment of goose-beaked whale responses to mid-frequency active sonar using a hierarchical hidden Markov model. [PDF]

Mov Ecol
DeRuiter SL, Falcone EA, Coates SN, Rone BK, Sweeney DA, Dolan KA, Jarvis SM, Andrews RD, Watwood SL, Schorr GS.   +9 more
europepmc   +1 more source

Clinical Validation of a QSP Model for ISB 2001, a Trispecific T Cell Engager to Support Optimal FIH Study Design in RRMM Patients

Clinical Pharmacology &Therapeutics, EarlyView.
ISB 2001 is a trispecific antibody that binds to two tumor‐associated antigens (TAA), CD38 and BCMA, and crosslinks to CD3 on T cells resulting in T cell‐mediated cytotoxicity of tumor cells expressing these TAAs. ISB 2001 is currently being tested in relapsed and/or refractory multiple myeloma (RRMM) patients in the first‐in‐human (FIH) TRIgnite‐1 ...
Vinu Chandralayam Ayyappa Menon, Tomomi Matsuura, Beata Holkova, Girish S. Gudi, Adam Drake, Maria Pihlgren, Piet H. van der Graaf, Sunitha GN, Andrew Garton, Mario Perro, Cyril Konto, Lida Pacaud   +11 more
wiley   +1 more source

Reduced Adult Survival Estimated in Areas of Decline of Harbour Seal Populations in Scotland. [PDF]

Ecol Evol
Arso Civil M, Tapp S, Dickens J, Langley I, Hiley HM, Terrapon M, Hague E, Hewitt RC, Cordes LS, Graham IM, Cheney BJ, Thompson PM, Hall A, Sparling CE.   +13 more
europepmc   +1 more source

A Study of High‐Emission Industries: How Policy, Strategy, and Technology Shape Corporate Social Responsibility Toward Carbon Neutrality

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The extant carbon neutrality (CN) literature largely offers macro‐ or meso‐level analyses, providing limited insights into implementation experiences that could inform granular policymaking and industry strategies. To address this gap, we examine the lived CN experiences of firms in the transportation, energy, manufacturing, and construction ...
Adeel Luqman, Shalini Talwar, Hawazen Almugren, Attila Kurucz, Enrico Battisti   +4 more
wiley   +1 more source

Domesticating the wild through escapees of two iconic mediterranean farmed fish species. [PDF]

Sci Rep
Toledo-Guedes K, Atalah J, Izquierdo-Gomez D, Fernandez-Jover D, Uglem I, Sanchez-Jerez P, Arechavala-Lopez P, Dempster T.   +7 more
europepmc   +1 more source

Breadth at the Helm: Generalist CEOs and Corporate ESG Performance‐Evidence From China

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Drawing on the Upper Echelons Theory and the Imprinting Theory, this study conjectures that generalist CEOs may have a stronger tendency to pursue environmental, social and governance (ESG) goals. We perform multiple regression analyses with observations of Shanghai and Shenzhen A‐share listed companies from 2010 to 2023 in order to explore ...
Shanmei Luo, Chaofan Jin, Hongling Han, You Zhang, Yuqi Li   +4 more
wiley   +1 more source

Global impacts of drifting fish aggregating devices on marine protected areas. [PDF]

Sci Adv
Schiller L, Villaseñor-Derbez JC, Lynham J, Worm B.   +3 more
europepmc   +1 more source

Fintech Policy and the Rise of Green Technological Inventions

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Technological transformation can enhance enterprises' green invention by promoting knowledge spillovers, alleviating financial constraints, and supporting innovative business models. Within this framework, our study investigates the effect of technological infrastructure construction on green technology invention, using the ‘Fintech China ...
Tao Huang, Qurat ul Ain, Tahir Yousaf, Kaiyang Zhong   +3 more
wiley   +1 more source

Black carbon emissions in Jordan: national inventory, climate and health implications (2022-2050). [PDF]

Environ Res Commun
Al-Shurafat A, Abdulla F, Sharafat A, Ghawanmeh A.   +3 more
europepmc   +1 more source