Results 51 to 60 of about 15,619,244 (298)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

A Synergy for Black Sea Regional Cooperation: Guidelines for an EU Initiative. CEPS Policy Briefs No. 105, 4 June 2006 [PDF]

open access: yes, 2006
This study advocates that the EU support a comprehensive, multi-stakeholder initiative to achieve synergy from regional cooperation in the wider Black Sea area.
Tassinari, Fabrizio
core  

A 2020 Vision for the Black Sea Region: the Commission on the Black Sea Proposes

open access: yes, 2010
The Black Sea region is coming into its own although it is at times a contested and dangerous neighbourhood. Despite heightened interest in the region its real priorities and needs are still being largely ignored by insiders and outsiders alike.
Aydın, Mustafa   +2 more
core   +1 more source

Geographic Variation in Life-History Traits of Black Sea Bass (Centropristis striata) During a Rapid Range Expansion

open access: yesFrontiers in Marine Science, 2020
The warming of the world’s oceans has resulted in the redistribution of many marine species globally. As species undergo range shifts, the expanding edge of the population often experiences novel environmental and demographic conditions that may result ...
Marissa D. McMahan   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Shore of the Black Sea

open access: yes, 2015
Shore of the Black Sea region, known as Karadeniz in Turkish, which is between Southeastern Europe and Western Asia, bounded by Europe, Anatolia and the Caucasus.135 film (36×24 ...
Gonnet-Bağana, Hatice
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Satellite Survey of Inner Seas: Oil Pollution in the Black and Caspian Seas

open access: yesRemote Sensing, 2016
The paper discusses our studies of oil pollution in the Black and Caspian Seas. The research was based on a multi-sensor approach on satellite survey data. A combined analysis of oil film signatures in satellite synthetic aperture radar (SAR) and optical
Marina Mityagina, Olga Lavrova
doaj   +1 more source

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