Results 61 to 70 of about 15,667,602 (298)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Synergy for Black Sea Regional Cooperation: Guidelines for an EU Initiative. CEPS Policy Briefs No. 105, 4 June 2006 [PDF]

open access: yes, 2006
This study advocates that the EU support a comprehensive, multi-stakeholder initiative to achieve synergy from regional cooperation in the wider Black Sea area.
Tassinari, Fabrizio
core  

A 2020 Vision for the Black Sea Region: the Commission on the Black Sea Proposes

open access: yes, 2010
The Black Sea region is coming into its own although it is at times a contested and dangerous neighbourhood. Despite heightened interest in the region its real priorities and needs are still being largely ignored by insiders and outsiders alike.
Aydın, Mustafa   +2 more
core   +1 more source

Geographic Variation in Life-History Traits of Black Sea Bass (Centropristis striata) During a Rapid Range Expansion

open access: yesFrontiers in Marine Science, 2020
The warming of the world’s oceans has resulted in the redistribution of many marine species globally. As species undergo range shifts, the expanding edge of the population often experiences novel environmental and demographic conditions that may result ...
Marissa D. McMahan   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Shore of the Black Sea

open access: yes, 2015
Shore of the Black Sea region, known as Karadeniz in Turkish, which is between Southeastern Europe and Western Asia, bounded by Europe, Anatolia and the Caucasus.135 film (36×24 ...
Gonnet-Bağana, Hatice
core   +1 more source

Terry M. Black, MCRD, to his family

open access: yes, 1964
Terry M. Black, writing from, MCRD, San Diego, California, to his family in Van Buren, Arkansas, in September 1964, writes about basic training and his time constraints for writing letters.
Black, Terry Moore, 1946-2022;
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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