Results 71 to 80 of about 109,948 (316)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Ancient Theatre and Performance Culture around the Black Sea
, 2019 This is the first study of ancient theatre and performance around the coasts of the Black Sea. It brings together key specialists around the region with well-established international scholars on theatre and the Black Sea, from a wide range of ...
Braund, David +2 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
, 2007 The Late Quaternary history of connection of the Black Sea to the Eastern Mediterranean has been intensely debated. Ryan, Pitman and coworkers advocate two pulses of outflow from the Black Sea to the world ocean at ~16–14.7 ky BP and ~11–10 ky BP ...
Aksu, A.E. +6 more
core
Migration, transnationalism and development on the Southeastern flank of Europe [PDF]
, 2013 The South-east Europe and Black Sea region presents a fertile terrain for examining recent international migration trends. A wide range of types of migration can be observed in this region: large-scale emigration in many countries, recent mass ...
Povrzanovic Frykman, Maja +7 more
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Hellenistic Period Watchtowers and Hillside Settlements Identified in “Vezirköprü” Surveys
Поволжская археологияVezirköprü, one of the largest districts of Samsun (Amisos), an important port city of the Black Sea, has been the scene of continuous settlement from the Eneolithic Period to the present day thanks to its fertile soils, rivers and its location on an ...
Temür Akın
doaj +1 more source
THE LEADERSHIP ROLE IN THE REGION - REGIONALISM - SECURITY EQUATION IN THE BLACK SEA
Bulletin of "Carol I" National Defense University, 2021 This study presents a few considerations about the leadership, the geopolitical and strategic importance of the Black Sea region, and potential threats or risks against security, stability, prosperity, and cooperation.
Mihai PANAIT
doaj
From the Allerød to the mid-Holocene: Palynological evidence from the south basin of the Caspian Sea [PDF]
, 2013 This article has been made available through the Brunel Open Access Publishing Fund. Copyright @ The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which
López-Merino, L +13 more
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source