Results 31 to 40 of about 3,228,711 (305)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

BLACK POLYPROPYLENE MULCH TEXTILE IN ORGANIC AGRICULTURE [PDF]

, 2010
Black polyethylene mulch is used for weed control in a range of crops under the organic system. The use of black polypropylene mulch is usually restricted to perennial crops.
Dvorak, Petr, Hajšlová, Jana, Hamouz, Karel, Kuchtova, Perla, Schulzová, Věra, Tomasek, Jaroslav   +5 more
core  

The Megamaser Cosmology Project: IV. A Direct Measurement of the Hubble Constant from UGC 3789

, 2013
In Papers I and II from the Megamaser Cosmology Project (MCP), we reported initial observations of water masers in an accretion disk of a supermassive black hole at the center of the galaxy UGC 3789, which gave an angular-diameter distance to the galaxy ...
Argon, Bonamente, Braatz, C. Henkel, C. M. V. Impellizzeri, C. Y. Kuo, Eisenstein, Freedman, Hogg, Humphreys, J. A. Braatz, J. J. Condon, K. Y. Lo, Komatsu, M. J. Reid, Masters, Reid, Riess, Sandage, Springob, Suyu   +20 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Co-creating knowledge in environmental policy development. An analysis of knowledge co-creation in the review of the significant residual impact guidelines for environmental offsets in Queensland, Australia

Environmental Challenges, 2021
Co-creation of knowledge in policy design and review processes is more likely to generate usable outcomes compared to a more traditional top-down approach.
Anthea Coggan, Josie Carwardine, Simon Fielke, Stuart Whitten   +3 more
doaj   +1 more source

Correlated dynamics of water and amphiphilic molecules in thin Newton black films [PDF]

, 2010
The dynamical properties of amphiphilics in Newton black films, as well as those of the water confined between the two charged hydrophilic surfaces, have been calculated via a series of molecular dynamic calculations in several films with different water
Di Napoli, Solange Mariel, Gamba, Z.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Contribuição à hidroquímica de drenagens no Município de Manaus - AM Contribution to the hydrochemistry of drainages in the municipality of Manaus-AM

Acta Amazonica, 2005
O rio Puraquequara, e seu afluente direito, o igarapé Água Branca, localizam-se fora da zona urbana de Manaus e estão com a bacia ainda protegida por floresta primária.
Adriana Maria Coimbra Horbe, Israel Leibnitz Ferreira Gomes, Sebastião Fonseca Miranda, Maria do Socorro Rocha da Silva   +3 more
doaj   +1 more source

Ultrastructure and Nutrient Content of Waste Sago and The Potential as Compost Block for Plant Growth Media [PDF]

, 2015
One alternative industrial waste that has not been widely used by the public is sago waste . Sago solid waste into compost that has brown to black coor . The purpose of this study was to analyze the structure of fresh sago waste , compost and compost dry
Prihastanti, Erma
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source