Results 131 to 140 of about 533,253 (303)

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

open access: yesAdvanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi   +8 more
wiley   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

open access: yesAdvanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing   +10 more
wiley   +1 more source

Understanding the identity choices of multiracial and multicultural Afro-European and Black women living in Germany [PDF]

open access: yes, 2007
This grounded theory study investigated the identity choices of highly achieving multiracial and multicultural Afro-European and Black immigrant women living in Germany and the role these choices played in their personal constructs of coping and self ...
Michel-Peres, Dominique
core  

An Integrative Strategy Delineates Modular Metabolic Remodeling and Potential Therapeutic Targets Across Metabolic Diseases

open access: yesAdvanced Science, EarlyView.
An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang   +10 more
wiley   +1 more source

ORBIT‐AMD: Ordinal Risk, Bilateral Imaging, and Trajectory Learning for Age‐Related Macular Degeneration in Multi‐Cohorts

open access: yesAdvanced Science, EarlyView.
Eligibility flow and real‐world AMD burden in the UKB retinal imaging cohort and TMUEH external‐validation cohort. Overview of the ORBIT‐AMD architecture, integrating retinal representation pretraining, bilateral eye‐graph modeling and concept bottleneck learning to support ordered risk, bilateral context, interpretable lesion concepts, longitudinal ...
Xuehao Cui   +3 more
wiley   +1 more source

Oxygen‐Assisted MOCVD Growth of Monolayer PtSe2 Films With Bandgap Opening for Semiconducting FET Channels

open access: yesAdvanced Science, EarlyView.
Monolayer PtSe2 films are successfully grown via optimized MOCVD, achieving uniform coverage over a 1.5 cm × 1.5 cm area. Oxygen‐assisted growth effectively removes carbon impurities, ensuring high film quality. Array‐level FETs based on monolayer PtSe2 channels demonstrate low off‐current and high ION/IOFF ratios, highlighting the potential of PtSe2 ...
Yuseok Kim   +22 more
wiley   +1 more source

Current Collector Engineering for New Efficient Bioresorbable Sodium‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
A bioresorbable Na‐ion battery is proposed with Mo or Mg thin‐film current collectors for temporary implants. Mo‐based batteries exhibit superior electrochemical performance and stable cycling compared with Mg counterparts. XPS was used to investigate the Mo/Mg surface oxidation.
Bincy Lathakumary Vijayan   +15 more
wiley   +1 more source

Black Women and Sexual Assault [PDF]

open access: yes, 2018
This factsheet published by the National Center on Violence Against Women in the Black Community gives data on black women and sexual assault in the United ...

core  

Hullo, Bu-Bye, Koko, Come In (Koleka Putuma)

open access: yesTydskrif vir Letterkunde, 2022
Gorata Chengeta
doaj   +1 more source

An Immediate‐Response Detection System for γ‐Hydroxybutyrate to Enhance Personal Safety in Social Environments

open access: yesAdvanced Science, EarlyView.
A graphene‐based electrical biosensor enables rapid and highly sensitive detection of GHB at 100 fm in both standard solutions and artificial urine, providing reliable point‐of‐need screening for drug‐facilitated sexual assault. The platform demonstrates strong selectivity, fast response, and a wide dynamic range, supporting accurate detection in ...
Jai Eun An   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy