Results 121 to 130 of about 1,846 (251)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Using genotype imputation to integrate Canola populations for genome-wide association and genomic prediction of blackleg resistance. [PDF]

BMC Genomics
Zhao H, MacLeod IM, Keeble-Gagnere G, Barbulescu DM, Tibbits JF, Kaur S, Hayden M.   +6 more
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Editorial: Epidemiology, prevention, and control of animal diseases in Kazakhstan. [PDF]

Front Vet Sci
Abdrakhmanov S, Perez AM.
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Editorial: Advancing livestock health: innovative vaccine strategies to combat antimicrobial resistance. [PDF]

Front Immunol
Uddin MB, Hewawaduge C.
europepmc   +1 more source

Corrigendum: Clostridium chauvoei, an Evolutionary Dead-End Pathogen

Frontiers in Microbiology, 2018
Lorenz Rychener, Saria In-Albon, Steven P. Djordjevic, Piklu Roy Chowdhury, Pamela Nicholson, Rosangela E. Ziech, Agueda C. de Vargas, Joachim Frey, Laurent Falquet   +8 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

A simple cost-effective method for purification of <i>Clostridium chauvoei</i> cell-surface proteins for detection of antibodies against blackleg disease vaccine. [PDF]

Vet Res Forum
Adib N, Zahmatkesh A, Bagheri M.
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source