Results 191 to 200 of about 1,876 (254)

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Pangenomics to understand prophage dynamics in the <i>Pectobacterium</i> genus and the radiating lineages of <i>Pectobacterium brasiliense</i>. [PDF]

Microb Genom
Pardeshi LA, van Duivenbode I, Pel MJC, Jonkheer EM, Kupczok A, de Ridder D, Smit S, van der Lee TAJ.   +7 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Ethnoveterinary medicinal plants and their utilization by indigenous and local communities of Dugda District, Central Rift Valley, Ethiopia. [PDF]

J Ethnobiol Ethnomed
Oda BK, Lulekal E, Warkineh B, Asfaw Z, Debella A.   +4 more
europepmc   +1 more source

<i>Pectobacterium punjabense</i> Causing Blackleg and Soft Rot of Potato: The First Report in the Russian Federation. [PDF]

Plants (Basel)
Vasilyeva AA, Evseev PV, Ignatov AN, Dzhalilov FS.   +3 more
europepmc   +1 more source

Ethnoveterinary medicinal plants in Aseko District, Arsi Zone, southeastern Ethiopia. [PDF]

Sci Rep
Jara JS, Maryo M, Girma Z.
europepmc   +1 more source

Factors affecting respiratory vaccination in Oklahoma cow-calf operations. [PDF]

Front Vet Sci
Harwell K, Hagerman AD, Raper KC, Shear H, Biggs R, Whitworth B.   +5 more
europepmc   +1 more source

Molecular characterization of a polymycovirus in Leptosphaeria biglobosa. [PDF]

Arch Virol
Samir NM, Locke-Gotel J, Urayama SI, El-Morsi AA, El-Sherbeny GA, Huang Y, Fitt BDL, Moriyama H, Coutts RHA, Kotta-Loizou I.   +9 more
europepmc   +1 more source