Results 131 to 140 of about 4,862,709 (265)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Wesreo : a blackleg resistant rapeseed

open access: yes, 1978
A new rapeseed variety, Wesreo, has recently been released after an unusually rapid and successful breeding programme by the Department of Agriculture.
Roy, N N
core   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Phoma stem canker (blackleg) of oilseed rape (canola) and other Brassica crops [PDF]

open access: yes
Phoma stem canker (blackleg) of oilseed rape, Brassicas and radish is caused by two closely-related fungi, Plenodomus lingam and P. biglobosus (formerly Leptosphaeria maculans and L. biglobosa). Plenodomus lingam is more aggressive but P. biglobosus can
King, K. M., West, J. S.
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Classic blackleg symptoms in a potato tuber

open access: yes, 1974
Classical blackleg symptoms in a potato tuber. Under ideal climatic conditions, disease will continue to spread.Host/Plant: Potato (Solanum tuberosum subsp.
Claflin, Larry
core  

Comparison of soy and meat peptones as ingredients of Clostridium chauvoei culture medium and their effect on immunogenicity and efficacy of the inactivated cultures

open access: yesBulgarian Journal of Veterinary Medicine
In immunised hosts, peptone from meat or animal sources may cause prion diseases or contain anti-genic peptides that potentially trigger anaphylactic and other adverse immune reactions.
L. Abdolmohammadi Khiav   +3 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Blackleg and its management in canola

open access: yes
Blackleg, caused by the fungus Leptosphaeria maculans, is the most common and serious disease of canola in Western Australia (WA). Blackleg can cause significant damage by infecting the cotyledons or first leaves early in the season, leading ultimately ...
Department of Primary Industries and Regional Development, Western Australia
core   +2 more sources

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

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