Results 91 to 100 of about 89,330 (310)

Environmental innocence and slow violence [PDF]

open access: yes, 2015
No description ...
Cecire, Natalia
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Race in Buenos Aires. Blackness, Whiteness, African Descent and Mestizaje in the White Capital City

open access: yesRuna, 2016
This article analyzes how racial categories are produced and reproduced in Buenos Aires, Argentina’s capital city. To that end, this article focuses on the cases of three Afro-Descendant porteña women who, by local standards, are fully white.
Lea Geler
doaj  

In Search of a Singular I: A Structurational Analysis of Passing [PDF]

open access: yes, 2005
It is easy to envision the socio-cultural phenomenon of passing as a relic of a bygone era, yet passing is markedly more. From a historical perspective, passing-as-white is a strategy of representation through which light-skinned, white-looking ...
Alesan, Dawkins Marcia
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Are Black Holes Black Bodies?

open access: yesNuclear Physics B, 1986
Abstract We give a new derivation for the properties of radiation appearing to an observer bounded in a space-time domain that has a horizon; this includes the Rindler case (constant accelerating frame) and the Schwarzschild solution (black hole). Because of the global nature of the quantum state, which inevitably extends to space beyond the horizon,
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Third World Themes in the International Politics of the Ceaușescu Regime or the International Affirmation of the ‘Socialist Nation’ [PDF]

open access: yes, 2018
The present article aims to offer a synoptic picture of communist Romania’s relations with Third World countries during the Ceaușescu regime. Within these relations, economic and geopolitical motivations coexisted along with ideological ones, thus making
Copilaș, Emanuel
core  

Letting the System Completely Absorb Me Would Be So Much Easier [PDF]

open access: yes, 2020
SchwarzRund is a Black Dominican queer femme feminist, active in intersectional education, Black German publishing and spoken word, empowerment around Fatness, Blackness, Queerness, and allyship, and critical media research.
Gramling, David, Ploschnitzki, Patrick
core  

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