Results 41 to 50 of about 11,906 (306)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Blackness in Britain [PDF]

open access: yes, 2016
Black Studies is a hugely important, and yet undervalued, academic field of enquiry that is marked by its disciplinary absence and omission from academic curricula in Britain.
Palmer, Lisa Amanda, Andrews, Kehinde
core   +1 more source

On Blackness, Liveliness, and What It Means to Be Human: Two Meditations

open access: yesJournal Committed to Social Change on Race and Ethnicity
In the Western history of ideas, light is conventionally associated with concepts such as rebirth, innovation, and creativity—exemplified by eras like the Enlightenment.
Wilson Kwamogi Okello
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Connecting Black Holes and Black Strings [PDF]

open access: yesPhysical Review Letters, 2005
Static vacuum spacetimes with one compact dimension include black holes with localised horizons but also uniform and non-uniform black strings where the horizon wraps over the compact dimension. We present new numerical solutions for these localised black holes in 5 and 6-dimensions.
Kudoh, Hideaki, Wiseman, Toby
openaire   +3 more sources

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters   +17 more
wiley   +1 more source

Obama and the politics of blackness: antiracism in the "post-black" conjuncture

open access: yes, 2010
This article sets out think about some of the challenges to U.S. antiracism heralded by Barack Obama's presidency. It begins by examining the relationship Obama negotiates with notions of blackness in his autobiographical writings, and it considers how ...
Ben Pitcher, Pitcher, B.
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Holding On and Letting Go in Kia LaBeija’s Self-Portraiture

open access: yesDisability Studies Quarterly, 2023
No abstract available.
Hilary Rasch
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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