A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair
An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret +6 more
wiley +1 more source
Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami +4 more
wiley +1 more source
Mechanisms of multidrug resistance in bladder cancer: the role of the nuclear membrane
Multidrug resistance (MDR) describes the phenomenon whereby cancer cellsexposed to a single cytotoxic drug develop cross resistance to numerous otherstructurally unrelated chemotherapeutics.
Featherstone, Jonathan Mark
core
Engineering Strain‐Stiffening Granular Hydrogels for 3D‐Printed Tissue‐Mimicry
A 3D‐printable strain‐stiffening double‐network granular hydrogel (SDGH) enables independent, region‐specific tuning of toe (EToe) and heel (EHeel) moduli through control of microgel packing and network composition. This platform replicates tissue‐like nonlinear mechanics and allows fabrication of high‐fidelity, multilayered aortic valves with ...
Hyeokju Chae +9 more
wiley +1 more source
Adverse events following intravesical Bacillus Calmette-Guérin therapy in Mater Dei Hospital, Malta [PDF]
Introduction: Intravesical administration of Bacillus Calmette-Guerin (BCG), following transurethral resection of bladder tumour, has been shown to reduce recurrence and progression in appropriately selected patients with non-muscle invasive bladder ...
Debattista, Christine +2 more
core
Modulated Raman spectroscopy for enhanced identification of bladder tumor cells in urine samples [PDF]
Standard Raman spectroscopy (SRS) is a noninvasive technique that is used in the biomedical field to discriminate between normal and cancer cells.
Herrington, C Simon +22 more
core +1 more source
A Pressure Microsensor Made of Parylene‐C for Use as Medical Implant
A monolithic parylene‐C pressure sensor with gold strain gauges provides 6.2 μV$\mu{\rm V}$·mmHg$\cdot{\rm mmHg}$−1$^{-1}$ sensitivity. The morphology of a sputtered thin film strain sensor is granular/columnar, which results in a high gauge factor of 7.5. Thermal bonding and parylene‐C coating create a hermetic cavity.
Ann‐Kathrin Klein +2 more
wiley +1 more source
A codesign multiobjective optimization framework was developed to enhance the morphology and controller of a snake‐like robot driven by artificial muscles. It improved planar locomotion, agility, and power efficiency. The approach optimized link geometry and controller gains, revealing that shorter muscles near joints and longer linkages maximize ...
Ayla Valles, Mahdi Haghshenas‐Jaryani
wiley +1 more source
REPORT OF THE BLADDER TUMOR STUDY GROUP IN OSAKA (2) STATISTICAL STUDY OF THE GRADE OF MALIGNANCY, STAGE OF INFILTRATION AND METHOD OF SURGICAL TREATMENT OF BLADDER TUMORS IN OSAKA [PDF]
This is a statistical study of the grade of malignancy, stage of infiltration, number of tumors (single or multiple), site and treatment, especially surgical, of 850 patients with bladder tumors who consulted the urological clinics belonging to the ...
大阪膀胱腫瘍研究会
core
IntroductionEnfortumab vedotin (EV) is an antibody drug conjugate approved for advanced urothelial cancer, consisting of a monomethyl auristatin E payload linked to a human monoclonal antibody targeting nectin-4.
Evangelia Vlachou +16 more
doaj +1 more source

