Results 161 to 170 of about 618,549 (318)

Diabetic bladder dysfunction is associated with bladder inflammation triggered through hyperglycemia, not polyuria

, 2018
Brian M Inouye,1 Francis M Hughes Jr,1,2 Huixia Jin,1 Robin Lütolf,3 Kunal C Potnis,1 Jonathan C Routh,1,4 Douglas C Rouse,5 Wen-Chi Foo,6 J Todd Purves1,2,4 1Department of Surgery, Division of Urology, Duke University Medical Center, Durham, NC ...
Routh JC, Purves JT, Inouye BM, Jin H, Foo WC, Lütolf R, Rouse DC, Potnis KC, Hughes FM Jr   +8 more
core  

Scalable Engineering of Bio‐Manufactured Extracellular Vesicles for Selective Delivery in Ovarian Cancer Patient‐Derived Models

Advanced Science, EarlyView.
Engineered extracellular vesicles displaying Ephrin‐B2 selectively target Ephrin‐B4–expressing ovarian cancer cells, enabling precise delivery in patient‐derived models. This scalable bio‐manufacturing platform reveals a versatile strategy to exploit Ephrin signaling for highly specific therapeutic payload delivery and motivates exploration of tailored
Nihar Godbole, Andrew Lai, Alexander Quinn, Marianne Gillard, Dominic Guanzon, Katherin Scholz‐Romero, Alexis Salas‐Burgos, Bastián Lillo Dapremont, Rohan Lourie, Naven Chetty, Richard Lobb, Kate Beecher, Amy E. McCart Reed, Kaltin Ferguson, Biao Sun, Yaowu He, John D. Hooper, Carlos Salomon   +17 more
wiley   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Older Kidney Transplant Patients Are Over Immunosuppressed Using Standard Protocols With Differential Sex-Based Complications

Journal of Transplantation
Inji Alshaer, Rachel K. Y. Hung, Sumoyee Basu, Gabrielle Goldet, Gareth Jones, Mark Harber, Raymond Fernando, Ciara N. Magee, Reza Motallebzadeh, Ben Caplin, Alan D. Salama   +10 more
doaj   +1 more source

Occult bladder injury in low displacement anterior-posterior compression pelvic fractures type I: a retrospective analysis of incidence and predictors. [PDF]

BMC Surg
Fahmy M, Shawky MA.
europepmc   +1 more source

“Membrane‐Guided” Repair Strategy: Precision Delivery of GGT1 Degrader for Targeted Repair and Regeneration of Spinal Cord Neurons

Advanced Science, EarlyView.
This study confirms that GGT1 is a key driver of neuronal ferroptosis following spinal cord injury. We developed NSCm@EA, a biomimetic delivery system coated with neural stem cell membranes, for precise delivery of enocyanin to injured neurons. By combining targeted delivery with ubiquitination degradation mechanisms, this system promotes MGRN1 ...
Tao Yang, Lei Ye, Peigen Xie, Tao Song, Jian Chen, Heng Zhao, Zhengshan Liu, Xi Chen, Jianing Ding, Xintian Ding, Ao Shao, Miaomiao Wu, Fengdong Zhao, Siyue Tao, Tao You   +14 more
wiley   +1 more source

Secondary Vesical Calculi in a Young Male With Post-Gunshot Neurogenic Bladder and Prior Colostomy: A Case Report. [PDF]

Clin Case Rep
Ammad SH, Meheshwari G, Ahmad W, Akram A, Amin MHJ.   +4 more
europepmc   +1 more source

Macrophage‐to‐Myofibroblast Transdifferentiation Contributes to Pulmonary Fibrosis via the MERTK‐SPP1‐SRC‐TKS5 Signaling Axis

Advanced Science, EarlyView.
MERTK is upregulated in fibrotic macrophages and regulates the expression and activity of SRC and TKS5 through SPP1, mediating transdifferentiation of macrophages‐to‐myofibroblasts (MMT) and promoting pulmonary fibrosis. The figure was created with BioRender.com.
Yungeng Wei, Hua Guo, Xiangsheng Yang, Xiao Xiao Tang   +3 more
wiley   +1 more source

Asymmetrically Coordinated Dual‐Atom Manganese Contrast Agents Enabling High‐Efficiency T1 Enhanced MRI for Precise Tumor Visualization

Advanced Science, EarlyView.
A novel dual‐atom manganese MRI contrast agent (Mn‐BN) with a unique asymmetric coordination geometry provided a promising platform for sensitive and specific tumor imaging. In mice model, Mn‐BN nanoparticles precisely functioned as both a primary tumor‐specific enhancer in subcutaneous models and a hepatocyte‐specific agent in liver metastases models ...
Ding Yang, Qing‐Yang Li, Jianli Liang, Gengyou Li, Nan Sun, Qianqian Song, Haitao Zhu, Xiaoting Li, Zechuan Li, Jiankai Dong, Weisheng Guo, Yafang Xiao, Chun‐Sing Lee, Ying‐Shi Sun   +13 more
wiley   +1 more source

Porcelain bladder with ascending ureteral calcifications and seminal vesicle calcifications: CT imaging features of advanced urogenital schistosomiasis. [PDF]

Radiol Case Rep
Mbodji I, Niang I, Diallo MA, Sow A, Ba S.   +4 more
europepmc   +1 more source