Results 221 to 230 of about 1,035,047 (359)

Exosomal CMTM4 Induces Immunosuppressive Macrophages to Promote Ovarian Cancer Progression and Attenuate Anti‐PD‐1 Immunotherapy

open access: yesAdvanced Science, EarlyView.
In ovarian tumors with high CMTM4 expression, exosomes transfer CMTM4 to macrophages, upregulating ICAM1 and promoting M2 polarization via p65 nuclear translocation. This suppresses immunity by increasing PD‐1 and Tregs while reducing CD8+ T cells.
Bo Yin   +12 more
wiley   +1 more source

Bladder Failure? [PDF]

open access: yesInternational Neurourology Journal, 2012
Khae Hawn Kim, Young Ho Kim
openaire   +3 more sources

A Generative AI‐Assisted Piezo‐MEMS Ultrasound Device for Plant Dehydration Monitoring

open access: yesAdvanced Science, EarlyView.
This study introduces a complementary metal–oxide–semiconductor (CMOS)‐compatible wearable piezoelectric micromachined ultrasound transducers (PMUTs) that sandwiches the leaf (PMUT–Leaf–PMUT, PLP) and employs generative artificial intelligence for real‐time analysis.
Kaustav Roy   +7 more
wiley   +1 more source

Identification and Evaluation of the Urinary Microbiota Associated With Bladder Cancer. [PDF]

open access: yesCancer Innov
Li N   +11 more
europepmc   +1 more source

Pyroptosis‐Inducing Platinum(IV) Prodrugs via GSDME Pathway for Chemoimmunotherapy and Metastasis Inhibition in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Three PtIV prodrugs MRP, DRP, and HRP are designed to induce pyroptosis in low GSDME‐expressing tumor cells via the Caspase‐3/GSDME pathway. By relaxing chromatin and reactivating GSDME, HRP can effectively induce pyroptosis, enhance pro‐inflammatory cytokine production, and exhibit potent antitumor effects.
Xinda Yang   +10 more
wiley   +1 more source

Repurposing Amiodarone for Bladder Cancer Treatment. [PDF]

open access: yesCancer Res Commun
Roa FJ   +21 more
europepmc   +1 more source

ROS‐Responsive Hydrogel for Localized Delivery of Nampt and Stat3 Inhibitors Exhibits Synergistic Antitumor Effects in Colorectal Cancer Through Ferroptosis Induction and Immune Microenvironment Remodeling

open access: yesAdvanced Science, EarlyView.
In this study, ferroptosis in colorectal cancer cells is induced by FK866 through the NAD⁺/STAT3/GPX4 pathway. To minimize systemic toxicity, a reactive oxygen species (ROS)‐responsive hydrogel is developed to co‐deliver FK866 and C188‐9, resulting in synergistic and localized antitumor effects.
Chenyang Ye   +14 more
wiley   +1 more source

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