Results 41 to 50 of about 479 (212)

Bladder exstrophy: An overview of the surgical management

Journal of Indian Association of Pediatric Surgeons, 2011
Background: The surgical management of urinary bladder exstrophy is challenging. This paper describes the personal experience in a tertiary care hospital over a period exceeding a quarter of a century.
Veereshwar Bhatnagar
doaj   +1 more source

EXPERIMENTAL EVALUATION OF AUTOLOGOUS GRAFTING USING TUNICA VAGINALIS PROPRIA FOR URINARY BLADDER AUGMENTATION IN DOGS [PDF]

Assiut Veterinary Medical Journal, 2014
A total number of 18 apparently healthy adult male mongrel dogs were used to evaluate tunica vaginalis propria as an autologus graft for bladder augmentation. Dogs were assigned into two groups.
EL-DAHARAWY, M.H., IBRAHIM A.
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Macrophage‐to‐Myofibroblast Transdifferentiation Contributes to Pulmonary Fibrosis via the MERTK‐SPP1‐SRC‐TKS5 Signaling Axis

Advanced Science, EarlyView.
MERTK is upregulated in fibrotic macrophages and regulates the expression and activity of SRC and TKS5 through SPP1, mediating transdifferentiation of macrophages‐to‐myofibroblasts (MMT) and promoting pulmonary fibrosis. The figure was created with BioRender.com.
Yungeng Wei, Hua Guo, Xiangsheng Yang, Xiao Xiao Tang   +3 more
wiley   +1 more source

Transition to adulthood with a bladder augmentation: histopathologic concerns

International Brazilian Journal of Urology
Aim: To investigate the histopathologic changes in native bladder and gastrointestinal segment, the relation between histopathologic changes, type of operation and the period passed over operation in patients with bladder augmentation.
Emil Mammadov, Sergulen Dervisoglu, Mehmet Elicevik, Haluk Emir, Yunus Soylet, S. N. Cenk Buyukunal   +5 more
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The effects of etiological factors on the results of augmentation enterocystoplasty: spinal cord injuries versus chronic tuberculosis cystitis

Urology Research and Practice, 2019
Objective: In our study, we aimed to compare the cystometric and clinic results of patients who underwent augmentation cystoplasty for the treatment of a contracted bladder, according to etiological factors such as chronic tuberculosis cystitis (CTC) and
Umut Gönülalan, Murat Koşan, Bülent Öztürk, Özgür Akdemir, Gürdal İnal, Mesut Çetinkaya   +5 more
doaj   +1 more source

ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief

Advanced Science, EarlyView.
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng, Changyu Liu, Qin Xia, Arndt F. Schilling, Jiawei Jiang, Renpeng Peng, Zixing Shu, Tian Ma, Danni Luo, Yaoyu Zhang, Yibo Fan, Xuyuan Zhang, Song Li, Kai Wang, Wentao Ke, Yuan Xiong, Yuanli Zhu, Fangzhi Mou, Jun Xiao, Hao Zhu   +19 more
wiley   +1 more source

Surgical Management of Neurogenic Sphincter Incompetence in Children

Frontiers in Pediatrics, 2019
We report on the results of a literature review regarding the indications and results of operations to increase bladder outlet resistance to achieve dryness in children with neurogenic sphincter incompetence (NSBD).
Barbara M. Ludwikowski, Jan-Christoph Bieda, Anja Lingnau, Ricardo González   +3 more
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WDR72 Promotes Neuroblastoma Stemness and Progression by Sequestering TRIM31‐Mediated Degradation of CBX8

Advanced Science, EarlyView.
This study unveiled that METTL14 mediates m6A modification of WDR72 mRNA to stabilize and enhance WDR72 expression, which disrupts TRIM31‐mediated ubiquitination of CBX8 protein and retards its degradation, finally the elevated CBX8 contributes to tumor stemness.
Huijuan Zeng, Zijie Ye, Manna Zheng, Jing Pan, Tianbao Tan, Jiliang Yang, Jiahao Li, Zhang Zhao, Tianzhu Long, Liyu Zhang, Gautam Sethi, Tianyou Yang, Chao Hu, Yan Zou   +13 more
wiley   +1 more source

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

Outcomes of Bladder Augmentation and Bladder Neck Reconstruction in children with Bladder Exstrophy: A Single-Institution prospective Study

SVU - International Journal of Medical Sciences
Background: Bladder augmentation utilizing gastrointestinal segments, combined with bladder neck reconstruction, represents a critical surgical approach in the management of children with bladder exstrophy, particularly for addressing urinary ...
Mohamed Abada Hassan , Ahmed Khairi Gabr , Sameh Mahmoud Shehata , Mohamed Abdelazim Shams , Ahmed Mohamed Oshiba   +4 more
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