Results 131 to 140 of about 5,312,533 (302)

A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes [PDF]

, 2019
Liang Wang, B. Smith, Nikolas G. Balanis, Brandon L. Tsai, Kim Nguyễn, Michael Cheng, Matthew B. Obusan, Favour N. Esedebe, Saahil J. Patel, Hanwei Zhang, Peter M. Clark, Anthony Sisk, Jonathan W. Said, Jiaoti Huang, Thomas G. Graeber, Owen N. Witte, Arnold I. Chin, Jung Wook Park   +17 more
openalex   +1 more source

Cancer-associated fibroblasts induce epithelial–mesenchymal transition of bladder cancer cells through paracrine IL-6 signalling

BMC Cancer, 2019
Cancer-associated fibroblasts (CAFs), activated by tumour cells, are the predominant type of stromal cells in cancer tissue and play an important role in interacting with neoplastic cells to promote cancer progression.
C. R. Goulet, A. Champagne, G. Bernard, Dominique Vandal, S. Chabaud, F. Pouliot, S. Bolduc   +6 more
semanticscholar   +1 more source

Immunotherapy for Bladder Cancer [PDF]

Klinicka Onkologie, 2017
Urothelial carcinoma is the most common urological malignancy. Nonspecific immunotherapy using the Bacillus Calmette-Guerin vaccine has long been the mainstay for the treatment of high-risk superficial bladder carcinoma in an adjuvant setting after transurethral endoscopic resection.
openaire   +2 more sources

MiR-10a-5p: A Promising Biomarker for Early Diagnosis and Prognosis Evaluation of Bladder Cancer

, 2021
Lei Yang, Hongfang Sun, Lin-Qing Guo, Hai-Bing Cao   +3 more
openalex   +2 more sources

Mouse and human urothelial cancer organoids: A tool for bladder cancer research

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Bladder cancer poses a big clinical challenge, particularly in advanced cases. Here we present a culture system for bladder cancer based on organoid culture technology. We have created a living biobank containing organoids grown from over 50
J. Mullenders, E. de Jongh, A. Brousali, Mieke Roosen, Jan P A Blom, H. Begthel, J. Korving, T. Jonges, O. Kranenburg, R. Meijer, H. Clevers   +10 more
semanticscholar   +1 more source

PHB promotes bladder cancer cell epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway

, 2023
Lijuan Jiang, Song‐Bin Guo, Zhongying Huang, Xin-Ling Li, Xiaohan Jin, Weijuan Huang, Xiao‐Peng Tian   +6 more
openalex   +1 more source

Singe intraoperative instillation of chemotherapy during radical cystectomy for bladder cancer: Oncological outcome and survival predictors [PDF]

, 2023
Jingtian Yang, Kaiwen Li, Yishan Zhang, Jintao Hu, Hao Liu, Wen Dong, Hai Huang, Tianxin Lin, Jian Huang, Wang He   +9 more
openalex   +1 more source

Somatic mutations render human exome and pathogen DNA more similar

, 2019
Immunotherapy has recently shown important clinical successes in a substantial number of oncology indications. Additionally, the tumor somatic mutation load has been shown to associate with response to these therapeutic agents, and specific mutational ...
Cristescu, Razvan, Ebrahimzadeh, Ehsan, Engler, Maggie, Tchamkerten, Aslan, Tse, David   +4 more
core   +1 more source

COL6A1 expression as a potential prognostic biomarker for risk stratification of T1 high grade bladder cancer: Unveiling the aggressive nature of a distinct non-muscle invasive subtype

, 2023
K. B. Kim, Young Joon Byun, Chuang-Ming Zheng, Sungmin Moon, Soo Jeong Jo, Ho Won Kang, Won Tae Kim, Yung Hyun Choi, Sung‐Kwon Moon, Wun‐Jae Kim, Xuan‐Mei Piao, Seok Joong Yun   +11 more
openalex   +1 more source

A first-in-class TIMM44 blocker inhibits bladder cancer cell growth

Cell Death and Disease
Mitochondria play a multifaceted role in supporting bladder cancer progression. Translocase of inner mitochondrial membrane 44 (TIMM44) is essential for maintaining function and integrity of mitochondria.
Lifeng Zhang, Xiaokai Shi, Lei Zhang, Yuanyuan Mi, Li Zuo, Shenglin Gao   +5 more
doaj   +1 more source