Results 291 to 300 of about 5,263,232 (399)

Perioperative chemotherapy use and related outcomes in muscle-invasive bladder cancer in Australia. [PDF]

BJUI Compass
Hiong A, Lynam J, Weickhardt A, Wong S, Sengupta S, Manohar P, Wong LM, Dundee P, Lawrentschuk N, Zhang AY, Anton A, Raghunath A, Gibbs P, Tran B.   +13 more
europepmc   +1 more source

RNA m1A methyltransferase TRMT61A promotes colorectal tumorigenesis by enhancing ONECUT2 mRNA stability and is a potential therapeutic target

Cancer Communications, EarlyView.
Abstract Background The role of N1‐methyladenosine (m1A) in cancer is poorly understood. Here we explored the function of RNA methyltransferase TRNA methyltransferase 61A (TRMT61A) in colorectal cancer (CRC) and its potential as a therapeutic target. Methods RNA m1A levels were assessed through liquid chromatography‐mass spectrometry.
Xiaoting Zhang, Na Qin, Fenfen Ji, Hao Su, Haiyun Shang, Hongyan Chen, Dan Huang, Qing Li, Jing Ren, Weixin Liu, Yifei Wang, Wei Kang, Jiabin Wu, Chi‐Chun Wong, Zongwei Cai, Matthew Tak Vai Chan, William Ka Kei Wu, Jun Yu, Huarong Chen   +18 more
wiley   +1 more source

Characterization of cancer-related fibroblasts in bladder cancer and construction of CAFs-based bladder cancer classification: insights from single-cell and multi-omics analysis. [PDF]

Front Immunol
Zhou Z, Chen Y, Wang Z, Yang S, Li Z, Shi R, Wang R, Liu K, Tang X, Li Q, Xu R.   +10 more
europepmc   +1 more source

Harnessing Nature: Computational and Experimental Insights Into Ipomoea obscura Metabolites for Bladder Cancer Therapy

Chemistry &Biodiversity, EarlyView.
ABSTRACT Ipomoea obscura (L.), a medicinal plant from the Convolvulaceae family, has been traditionally used to treat various ailments. This study evaluated the in vitro cytotoxicity of its ethanolic leaf extract against human bladder cancer T24 cells and investigated its phytochemical constituents through computational methods.
Saravana Prabha Poochi, Rajamanikandan Sundarraj, Manikandan Vani Raju, Meenakshi Kaniyur Chandrasekaran, Rathi Muthaiyan Ahalliya, Chella Perumal Palanisamy, Gopalakrishnan Velliyur Kanniappan, Benod Kumar Kondapavuluri, Muthu Thiruvengadam   +8 more
wiley   +1 more source

Targeting Cryptochromes in Chronic Diseases

Cell Biology International, EarlyView.
ABSTRACT The circadian clock generates 24‐h molecular rhythms through transcription–translation negative feedback loops (TTFLs) and regulates daily physiological processes such as sleep–wake cycles, body temperature, hormone secretion, metabolism, and immune function.
Takuro Toda, Tsuyoshi Hirota
wiley   +1 more source

The natural history and twenty year followups in bladder cancer and its management in a primary health care facility

, 1977
Harvey A. Gilbert, John Logan, J.F. Cooper, Alexander Kagan, Karen Cove, H. I. Freedman, Thomas Muldoon, Yvonne Lonni, Michael H. Fox, Norman Nadel, John W. Rowe, Herman Nussbaum, Paul Po Ling Chan   +12 more
openalex   +1 more source

Repurposing Amiodarone for Bladder Cancer Treatment. [PDF]

Cancer Res Commun
Roa FJ, Roubelakis M, Paschidis K, van Creij NCH, Handle F, Makridakis M, Narayanasamy S, Balaur IA, Tserga A, Vlahou A, Santer FR, Holm PS, Hoffmann M, Puhr M, Mokou M, Frantzi M, Schneider R, Latosinska A, Mischak H, Satagopam V, Culig Z, Pichler R.   +21 more
europepmc   +1 more source

Synergistic Reduction of Breast Cancer Cell Viability and Aggressiveness Through Dual Inhibition of APE1 Redox Function and STAT3 Signaling

Cell Biology International, EarlyView.
ABSTRACT Aggressiveness and resistance to treatments are significant problems in cancer management. In this scenario, searching for new pharmacological targets for therapies is essential. The APE1 redox domain coactivates transcription factors that favor cancer malignancy. One of APE1's targets, STAT3, coordinates the transcription of genes involved in
Mariana Moreno de Sousa Rodrigues, Priscyanne Barreto Siqueira, Ana Clara Cavallo Dobao, Maria Eduarda Barbosa Mourão, Bruno Ricardo Barreto Pires, Adenilson de Souza da Fonseca, Ísis Salviano Soares de Amorim, Andre Luiz Mencalha   +7 more
wiley   +1 more source

A CASE OF UNSYNCHRONOUS MULTIPLE CANCER OF THE ESOPHAGUS AND THE BLADDER

, 1979
Yoshitaka Nakata, K Nabeya, Tateo Hanaoka, Kimio Onozawa, Shigen Ri, Yuji Arai, Teiji Motojima, Tetsuya Nyumura, Hisahito MIYAJIMA   +8 more
openalex   +2 more sources