Results 301 to 310 of about 530,197 (354)

Ubiquitination in cancer: mechanisms and therapeutic opportunities

Cancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu, Xu Zhang, Waner Liu, Zhe Zhou, Siyu Xiong, Jie Li, Xiang Chen, Cong Peng   +7 more
wiley   +1 more source

GSK343, an inhibitor of EZH2, prevents acquired cisplatin resistance in bladder cancer. [PDF]

Mol Genet Genomics
He L, Liu P.
europepmc   +1 more source

NAT10 regulates tumor progression and immune microenvironment in pancreatic ductal adenocarcinoma via the N4‐acetylated LAMB3‐mediated FAK/ERK pathway

Cancer Communications, EarlyView.
Abstract Background N‐acetyltransferase 10 (NAT10) was reported to be associated with the immune microenvironment in several cancers. However, it is not known in pancreatic ductal adenocarcinoma (PDAC). This study aimed to elucidate the roles and mechanisms of NAT10 in tumor malignancy and the tumor microenvironment (TME) in PDAC.
Enhong Chen, Qin Wang, Leisheng Wang, Zebo Huang, Dongjie Yang, Changyong Zhao, Wuqiang Chen, Shuo Zhang, Shuming Xiong, Youzhao He, Yong Mao, Hao Hu   +11 more
wiley   +1 more source

Epigenetic dysregulation-induced metabolic reprogramming fuels tumor progression in bladder cancer. [PDF]

Front Mol Biosci
Zhang J, Fan X, Xu X, Han Y, Yu W, Yang B, Chen Y, Zhang S.   +7 more
europepmc   +1 more source

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

Cancer Communications, EarlyView.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu, Yingqi Zhao, Xin Zhang, Yuanhe Wang, Qiuchen Chen, Mingrong Zhang, Huan Sheng, Yuying Zhang, Jinyu Guo, Jun Li, Yuxuan Fan, Ziqing Wang, Yalun Li, Haoran Wang, Minjie Wei, Xiaoyun Hu, Huizhe Wu   +16 more
wiley   +1 more source

Survival Outcomes in Bladder Cancer: An Ambispective Study of Patients Undergoing Radical Cystectomy. [PDF]

Cureus
Ranjith S, Thomas Jacob A, Augustine P, K C, Muralee M, Joseph J, Radhakrishnan N, Krishna Km J.   +7 more
europepmc   +1 more source

From exposure to innovation: decoding aromatic amines' role in bladder cancer mechanisms. [PDF]

Discov Oncol
Xu H, Li J, Peng S, Bai Y, Tang W.
europepmc   +1 more source

Sex differences in bladder cancer: understanding biological and clinical implications. [PDF]

Biol Sex Differ
Chaudhary P, Singha B, Abdel-Hafiz HA, Velegraki M, Sundi D, Satturwar S, Parwani AV, Grivennikov SI, You S, Goodridge HS, Ma Q, Chang Y, Ma A, Zheng B, Theodorescu D, Li Z, Li X.   +16 more
europepmc   +1 more source

Lymphovascular Invasion Is a Predictor of Clinical Outcomes in Bladder Cancer Patients Treated with Radical Cystectomy. [PDF]

J Clin Med
Dulf DV, Burnar AL, Dulf PL, Matei DR, Hendea RM, Andraș I, Grecea M, Bungărdean C, De Leo A, Ciuleanu TE, Crișan N, Coada CA.   +11 more
europepmc   +1 more source

Bladder cancer subtypes exhibit limited plasticity across different microenvironments and in metastases. [PDF]

Exp Hematol Oncol
Bernardo C, Chattopadhyay S, Andersson N, Eriksson P, Medle B, Tran L, Dain Marzouka NA, Mattsson A, Zadoroznyj A, Larsson M, Liedberg F, Höglund M, Sjödahl G.   +12 more
europepmc   +1 more source