Results 161 to 170 of about 571,573 (299)

Diabetes‐Induced Dysregulation of Purinergic Signaling in the Bladder Mucosa: Accelerated ATP Hydrolysis and Impaired Adenosine Uptake Promote Underactive Bladder Phenotype

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Objective To explore molecular mechanisms underlying excessive extracellular adenosine (ADO) accumulation in the bladder lamina propria (LP) of mice with type 2 diabetes (T2D) induced by a high‐fat, high‐sucrose diet (HFHSD), conceivably leading to bladder underactivity.
Mahsa Borhani Peikani   +2 more
wiley   +1 more source

Functional Roles of Adenosine A2B and A3 Receptor Subtypes in the Bladder of Male Rats With A2B Receptor Deletion or Bladder Outlet Obstruction

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Purpose To investigate the adenosine receptor (AR) mechanism underlying bladder outlet obstruction (BOO)‐related bladder dysfunction, we examined the expression level of AR subtypes in bladder tissues, and the effects of AR subtypes A2B & A3 modulation on bladder activity using male BOO rats, and Dahl rats with A2B receptor deletion. Materials
Masahiro Kurobe   +8 more
wiley   +1 more source

Fear‐Avoidance and Overactive Bladder: Toward a Mechanism‐Informed Model of Care

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims Overactive bladder (OAB) is associated with substantial psychological burden, yet existing biopsychosocial frameworks acknowledge that psychological factors shape outcomes without explaining the cognitive and behavioral mechanisms through which that influence operates.
Rupal M. Patel, Andrea Wood
wiley   +1 more source

Managing Primary Bladder Neck Obstruction in Females: Is Bladder Neck Incision the Best Way Forward? [PDF]

open access: yesCureus
Bhatia S   +7 more
europepmc   +1 more source

Diagnosis of Urethral Resistance in Men: 70 Years of History

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Background and Aims The urethral resistance (UR) is one of the key outcomes of the urodynamic pressure‐flow study (PFS) in men. Combined with a clinical meaningful cut‐off point, urodynamic bladder outflow obstruction (BOO) can be determined. This characterization of BOO provides guidance in the management of lower urinary tract symptoms (LUTS)
Wouter van Dort   +2 more
wiley   +1 more source

Enterovirus infections in children

open access: yesPediatric Investigation, EarlyView.
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen   +11 more
wiley   +1 more source

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