Results 41 to 50 of about 106,669 (305)

Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare

Advanced Robotics Research, EarlyView.
Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin, Jimin Kim, Inho Kim, Bong Hoon Kim   +3 more
wiley   +1 more source

Urethral duplication with unusual cause of bladder outlet obstruction

Indian Journal of Urology, 2016
A 12-year-old boy presented with poor flow and recurrent urinary tract infections following hypospadias repair at the age of 3 years. The evaluation revealed urethral duplication with a hypoplastic dorsal urethra and patent ventral urethra.
Vivek Venkatramani, Arun Jacob Philip George, J Chandrasingh, Arabind Panda, Antony Devasia   +4 more
doaj   +1 more source

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng, Mengmeng Wang, Kang Wang, Zhuo Xing, Yulong Hong, Tongtong Li, Geng Zong, Chong Yang, Dan Zhang, Zhangling Chen, Xin Jin   +10 more
wiley   +1 more source

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

Advanced Science, EarlyView.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon, Maria Tsiokou, Patricia Marqués, Enriqueta Rodríguez‐Diaz, Hazel Ang, Federico Pietrocola, Christian G. Riedel   +6 more
wiley   +1 more source

Bladder exstrophy: Comparison of anatomical bladder neck repair with innervation preserving sphincteroplasty versus Young-Dees-Leadbetter bladder neck reconstruction

Journal of Indian Association of Pediatric Surgeons, 2013
Aim: To evaluate the outcome of innervation preserving sphincteroplasty along with anatomical bladder neck reconstruction (IPS-ABNR) compared to classic Young-Dees-Leadbetter (YDL) bladder neck reconstruction in exstrophy with insufficient bladder ...
Archika Gupta, Shiv Narain Kureel, Ashish Wakhlu, Jiledar Rawat   +3 more
doaj   +1 more source

Significance of 4D US parameters for the clinical treatment of female patients with stress urinary incontinence

Frontiers in Surgery, 2023
BackgroundStress urinary incontinence (SUI) that has been associated with abnormal pelvic floor muscle function or morphology is a common condition.
Changqin Jiang, Changqin Jiang, Changqin Jiang, Song Zhang, Song Zhang, Jing Chen, Jing Chen, Yangyang Zhang, Yangyang Zhang, Yangyang Zhang, Keke Cai, Keke Cai, Keke Cai, Wei Chen, Wei Chen, Wei Chen, Yuanyuan Wu, Chaozhao Liang, Chaozhao Liang, Chaozhao Liang   +19 more
doaj   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Bladder augmentation and bladder neck reconstruction in bladder exstrophy patients: a single center experience

BMC Urology
Background Bladder augmentation with gastrointestinal tissue accompanied by bladder neck repair are important tools for pediatric surgeons in the management of children with Bladder exstrophy for urinary incontinence.
M Abada, A Khairi, S Shehata, M Abouheba, A Oshiba   +4 more
doaj   +1 more source

83 - The first European experience of stepwise robotic female AUS implantation on 3D printed and porcine models as procedure-based physical simulator

Continence
Introduction: Robot-assisted female AMS-800 Artificial Urinary Sphincter (AUS) implantation is a challenge surgery that needs to be trained well. The lack of procedure-based simulation model except cadaver led us to use porcine model for training ...
E Huri, S Aydın, H Hashim, B Marnique, İ Tatar, A Canda, B Peyronette   +6 more
doaj   +1 more source