Results 201 to 210 of about 433,450 (245)

Perioperative Safety and Long-Term Oncological Outcomes of En Bloc Resection of Bladder Tumor: A Multicenter Real-World Study of 668 Patients. [PDF]

open access: yesInt J Urol
Yanagisawa T   +12 more
europepmc   +1 more source

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Multi‐omics–driven precision medicine

open access: yesiMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li   +20 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

open access: yesInterdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li   +7 more
wiley   +1 more source

Diagnosis by Resolution: Ultrasound Follow‐Up of Neonatal Polypoid Cystitis Mimicking Botryoid Rhabdomyosarcoma

open access: yesJournal of Clinical Ultrasound, EarlyView.
In neonatal bladder masses, benign inflammatory conditions like polypoid cystitis can mimic malignancy on ultrasound. In stable neonates with evidence of infection, short‐interval ultrasound follow‐up after antibiotic therapy allows “diagnosis by resolution.” This conservative approach safely avoids unnecessary invasive procedures while maintaining ...
Davide Meneghesso   +4 more
wiley   +1 more source

Induction and characterization of neoplastic bladder tumors in a transgenic porcine model. [PDF]

open access: yesBladder Cancer
Aulitzky A   +17 more
europepmc   +1 more source

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