Results 171 to 180 of about 1,097,882 (270)

WDR72 Drives Esophageal Squamous Cell Carcinoma Progression by Inhibiting Autophagy via the PI3K/Akt/mTOR Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy with a high rate of recurrence and metastasis, necessitating the identification of novel therapeutic targets. WD repeat‐containing protein 72 (WDR72) has been linked to various cancers, but its specific biological function and underlying mechanism in ESCC remain largely ...
Hao Wu, Zhong‐Xiang Jiang, Zheng Jiang
wiley   +1 more source

GlideRite® rigid stylet vs Flex-it® articulated stylet for intubation with videolaryngoscopy in patients with semi-rigid cervical collar: a randomized trial. [PDF]

open access: yesBraz J Anesthesiol
Nguyen JV   +10 more
europepmc   +1 more source

Multicentric development and validation of a fully automated artificial intelligence system for planning medial open wedge high tibial osteotomy on weight‐bearing anterior‐posterior long leg radiographs: The ISAKOS John Joyce Award 2025

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Preoperative planning, currently performed by orthopaedic surgeons (OS), is essential for successful osteotomy, but is labour‐intensive and error‐prone. As such, there is significant potential in the use of automated artificial intelligence (AI) algorithms to augment the abilities of OS in managing lower extremity pathologies in a high‐
Marco‐Christopher Rupp   +13 more
wiley   +1 more source

Invention of the Flexible Fiberoptic Nasopharyngolaryngoscope: Perspectives From the East

open access: yesThe Laryngoscope, EarlyView.
The fiberoptic nasopharyngolaryngoscope was developed in 1967 by Drs. Masayuki Sawashima, Hajime Hirose, and Osamu Fujimura at the University of Tokyo's Research Institute of Logopedics and Phoniatrics (RILP), building on Dr. Shigeto Ikeda's 1962 fiberoptic bronchoscope during Japan's postwar surge in technological innovation.
Carolyn J. Khoury   +7 more
wiley   +1 more source

Polycarbonate Vitrimers and Dynamic Co‐Networks From Epoxide/Carbon Dioxide Copolymerization

open access: yesMacromolecular Rapid Communications, EarlyView.
This work demonstrates how CO2‐derived poly(propylene carbonate) and poly(cyclohexene carbonate) backbones influence vitrimer thermo‐mechanical behavior. By tuning backbone composition, epoxide crosslinker chemistry and blend ratios, the crosslinked materials span a wide property window, from highly extensible to stiff, glassy networks, establishing an
Satej S. Joshi   +3 more
wiley   +1 more source

Mass Spectrometry Imaging–Guided Proteomics, an Emerging Frontier in Spatial Biology

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Spatial heterogeneity is a defining feature of tissue organization, yet conventional proteomic analysis provides limited information about the spatial origins of identified proteins. Spatially guided proteomics addresses this limitation by using tissue imaging techniques to select regions of interest (ROIs) for localized analysis by liquid ...
Kenneth Weke   +4 more
wiley   +1 more source

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