Results 91 to 100 of about 1,608,065 (365)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

Diesel Buses, Oil Prices and Premature Deaths from Particulate Matter: Understanding the Connections, Exploring Solutions [PDF]

open access: yes, 2000
In 2000 the Environmental and Energy Study Institute hosted a briefing to discuss the complex issues surrounding diesel buses and alternative-fuel buses.
Randi Blank
core  

Regulatory Use of Essential Performance Characteristics of Medical Devices for In Vitro Diagnostics

open access: yesЗдоровье мегаполиса
The article covers the performance characteristics of in vitro diagnostics (IVD) medical devices, the systematic approaches to specify the performance characteristics of IVD medical devices, the review of regulations with specified performance ...
V. V. Maslennikov
doaj   +1 more source

Printed Integrated Logic Circuits Based on Chitosan‐Gated Organic Transistors for Future Edible Systems

open access: yesAdvanced Functional Materials, EarlyView.
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco   +8 more
wiley   +1 more source

Biodegradable and Recyclable Luminescent Mixed‐Matrix‐Membranes, Hydrogels, and Cryogels based on Nanoscale Metal‐Organic Frameworks and Biopolymers

open access: yesAdvanced Functional Materials, EarlyView.
The study presents biodegradable and recyclable mixed‐matrix membranes (MMMs), hydrogels, and cryogels using luminescent nanoscale metal‐organic frameworks (nMOFs) and biopolymers. These bio‐nMOF‐MMMs combine europium‐based nMOFs as probes for the status of the materials with the biopolymers agar and gelatine and present alternatives to conventional ...
Moritz Maxeiner   +4 more
wiley   +1 more source

Developing a practical guide for teaching histology: an evaluation of the didactic components [PDF]

open access: yes, 2013
The Didactic Guide is a valuable tool complementing and making learning more dynamic. It is done using creative didactic strategies that simulate the presence of the tutor and generate a dialogue in order to offer students different possibilities to ...
Alaminos, Miguel   +7 more
core   +1 more source

Highly Sensitive Electrochemical Biosensor Based on Hairy Particles with Controllable High Enzyme Loading and Activity

open access: yesAdvanced Functional Materials, EarlyView.
For the first time, a highly sensitive electrochemical biosensor based on SiO2‐based hairy particles with a grafted PDMAEMA polymer brush containing a quantifiable and large amount of immobilized Laccase is reported. The fabricated biosensor exhibits a sensitivity of 0.14 A·m⁻¹, a limit of detection (LOD) of 0.1 µm, and a detection range of 0.3–750 µm,
Pavel Milkin   +7 more
wiley   +1 more source

ANALYSIS OF PROCESSING OF ARCHED FORMING ELEMENTS OF ROLLERS OF ROLLING PRESSES

open access: yesВесці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук, 2016
A version of forming elements for rollers of rolling presses in the form of circumferential slots with a concave profile, forming arched lugs is proposed.
V. Ya. PRUSHAK   +2 more
doaj  

Blank variability in coulometric measurements of dissolved inorganic carbon [PDF]

open access: yesOcean Science
Marine dissolved inorganic carbon (DIC) is by far the largest pool of carbon in the Earth surface system that exchanges with the atmosphere on human-relevant timescales.
M. P. Humphreys, S. Ossebaar
doaj   +1 more source

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