Results 141 to 150 of about 445,054 (335)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Curvature Effects on the Electromagnetic Force, Efficiency, and Heat Transfer of a Weak Low Profile Magneto-Hydrodynamic Blanket Propulsion System

open access: yesJournal of Applied Fluid Mechanics, 2017
The present study concerns the numerical assessment of the effects of longitudinal and lateral curvature of a flexible low profile magneto-hydrodynamic blanket on its thrust, performance, and heat transfer.
M. A. Feizi Chekab, P. Ghadimi
doaj  

Loss of power accident analysis for the HCCR blanket

open access: yesNuclear Engineering and Technology
The blanket system is a crucial element in nuclear fusion power generation, tasked with tritium production and the efficient dissipation of the high thermal flux from the tokamak. Korea is in the process of developing the Helium Cooled Ceramic Reflector (
Hyung Gon Jin   +3 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Research on Simplified Nursery and Labor-Saving Mechanized Transplanting Technologies to Improve Rice Production Efficiency in Southern China

open access: yesAgronomy
Mounting labor shortages and rising operational costs are threatening the sustainability of mechanized rice production in Southern China, underscoring the urgent need for innovations that reduce labor inputs during nursery preparation and transplanting ...
Haoyu Wang   +8 more
doaj   +1 more source

The McCarran-Walter Act:A Contradictory Legacy on Race, Quotas, and Ideology [PDF]

open access: yes, 2004
The McCarran-Walter Act of 1952 ended the blanket exclusion of immigrants based on race and created the foundation for current immigration law, but imposed a racialized immigration quota system and new ideological grounds for ...
Alicia J. Campi
core  

Brooks Blanket [PDF]

open access: yesJournal of the Royal Army Medical Corps, 1981
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Silica final lenses under HiPER laser fusion reactor operation conditions

open access: yes, 2011
We have studied the thermo-mechanical response and atomistic degradation of final lenses in HiPER project. Final silica lenses are squares of 75 × 75 cm2 with a thickness of 5 cm.
Alvarez Ruiz, Jesus   +5 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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