Results 151 to 160 of about 364,728 (300)

Identification of Elite R-Gene Combinations against Blast Disease in Geng Rice Varieties. [PDF]

Int J Mol Sci, 2023
Gao P, Li M, Wang X, Xu Z, Wu K, Sun Q, Du H, Younas MU, Zhang Y, Feng Z, Hu K, Chen Z, Zuo S.   +12 more
europepmc   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

HUBUNGAN KARAKTERISTIK JARINGAN DAUN DENGAN TINGKAT SERANGAN PENYAKIT BLAS DAUN (Pyricularia oryzae Cav.) PADA BEBERAPA GENOTIPE PADI (Oryza sativa L.)

Jurnal HPT (Hama Penyakit Tumbuhan), 2013
Blast is the oldest disease in the world (Valent, 2004). In 1975 according to Chin, blast could be found in more than 85 countries of rice field include Asia, America Latin and Africa.
Ina Mustika Dewi, Abdul Cholil, Anton Muhibuddin   +2 more
doaj  

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

RENAL‐CHIP: Rejection Evaluation via Non‐Invasive Analysis of Circulating Podocytes With Herringbone‐Chip Isolation Platform

Advanced Science, EarlyView.
RENAL‐CHIP converts 1 mL of peripheral blood into a biopsy‐equivalent readout of renal‐allograft fate. By magnetic capture and release of donor‐derived circulating podocytes through a herringbone microfluidic chip, 84% capture, 96% release and single‐cell RNA evidence of rejection‐specific immunity are achieved.
Juan Song, Yilong Liu, Zeyuan Zheng, Ming Zhu, Yuning Zou, Pei Liu, Yue Zheng, Xiyuan Yu, Jianzhong Zheng, Chen Shao, Huimin Zhang, Chaoyong Yang   +11 more
wiley   +1 more source

Adult-plant resistance of upland rice genotypes against blast (Pyricularia oryzae Cavara) in Metekel Zone, North West Ethiopia

Discover Agriculture
Rice blast disease, caused by Pyricularia oryzae Cavara is one of the main biotic factors and the most destructive of all rice diseases impeding rice production in more than 85 countries in the world.
Tesfaye Gudisa Waktola, Ararsa Leta, Desta Abebe   +2 more
doaj   +1 more source

NUDT21 Drives T‐Cell Acute Lymphoblastic Leukemia Through Dual Regulation of Alternative Polyadenylation and Transcriptional Activation

Advanced Science, EarlyView.
In summary, our study defines a coordinated oncogenic model in which NUDT21 integrates alternative polyadenylation–dependent UBE2D3 stabilization and transcriptional activation to sustain MYC‐driven T‐ALL cell survival, thereby establishing NUDT21 as a central regulatory node and a promising therapeutic target.
Conglian Qiu, Jianwei Wang, Zhiheng Li, Qi Ji, Hui Zhang, Qinyi Zhang, Senlin Zhang, Juanjuan Yu, Yanfang Tao, Yijun Wu, Chunxia Shi, Zong Zai, Zimu Zhang, Yizhen Li, Zhenjiang Bai, Shaoyan Hu, Jian Pan, Yang Yang, Shuiyan Wu   +18 more
wiley   +1 more source

Rice leaf endophytic Microbacterium testaceum: Antifungal actinobacterium confers immunocompetence against rice blast disease. [PDF]

Front Microbiol, 2022
Patel A, Sahu KP, Mehta S, Balamurugan A, Kumar M, Sheoran N, Kumar S, Krishnappa C, Ashajyothi M, Kundu A, Goyal T, Narayanasamy P, Kumar A.   +12 more
europepmc   +1 more source

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

Advanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui, Kotone Nakagawa, Takumi Tateno, Ayaka Dan, Dexin Meng, Yoshihiro Omori, Soma Tomihara, Suzuri Okamoto, Shigeru Sato, Motokazu Tsujikawa   +9 more
wiley   +1 more source

Phenotypic and Genotypic screening of fifty-two rice (Oryza sativa L.) genotypes for desirable cultivars against blast disease. [PDF]

PLoS One, 2023
B J, Hosahatti R, Koti PS, Devappa VH, Ngangkham U, Devanna P, Yadav MK, Mishra KK, Aditya JP, Boraiah PK, Gaber A, Hossain A.   +11 more
europepmc   +1 more source