Results 151 to 160 of about 80,415 (249)

ER‐Localized Deadenylase PNLDC1 Suppresses Colorectal Cancer Progression by Targeting the mRNA Decay of TUBB4B

Exploration, EarlyView.
The deficiency of PNLDC1 exacerbates the advancement of CRC. PNLDC1 interacts with TUBB4B mRNA to regulate the p53–p21–CDK2–cyclin E2 pathway, thereby influencing the G2/M phase of the cell cycle. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related mortality, highlighting the urgent need for novel therapeutic strategies.
Lexin Liu, Yuelin Guan, Yuzhou Qin, Guiping Chen, Guozhen Wang, Xiang Yan, Xue Li, Lei Sun, Wei Yu, Shi Ouyang, Zhichao Ma, Zihao Xu, Zhongkai Cao, Fan Yu, Tong Zhou, Ziyou Luo, Xiangjun Chen, Yongbin Yan, Lidan Hu   +18 more
wiley   +1 more source

CRISPR/Cas9-Mediated Editing of <i>Bsr-d1</i> and <i>Pi21</i> Enhances Blast Resistance in a High-Quality Rice Maintainer Line. [PDF]

Plants (Basel)
Lan K, Yuan L, Zhao D, Ma X, Yang J, Wu H, Liu F, Chen S, Li R.   +8 more
europepmc   +1 more source

AI‐enabled biomimetic flexible pressure sensors for high‐precision gait monitoring and rehabilitation assessment

FlexMat, EarlyView.
A biomimetic multilayer capacitive sensor‐integrated insole enables high‐resolution plantar pressure mapping for intelligent gait analysis. Featuring ultrahigh sensitivity, wide detection range, and long‐term stability, the system leverages AI algorithms to decode spatiotemporal pressure signals, achieving accurate recognition of postoperative ...
Yingchun Li, Yarong Ding, Kaixin Lei, Yuze Zhang, Zhenhua Lin, Jiachun Sun, Kaitai Guo, Yang Zheng, Shaozhe Tan, Xuesi Zhang, Xinyue Li, Yue Hao, Xiangning Li, Yannan Liu, Jingjing Chang   +14 more
wiley   +1 more source

History of near-isogenic lines carrying genes for resistance to bacterial blight and blast in rice (Oryza sativa L.). [PDF]

Plant Genome
Schepler-Luu V, Telebanco-Yanoria MJ, Saito H, Vera Cruz CM.   +3 more
europepmc   +1 more source

Highly conductive and robust epidermal dry electrode for long‐term interval biopotential monitoring

FlexMat, EarlyView.
A freestanding PVA‐PBFDO conductive dry electrode combines high conductivity, flexibility, and environmental stability to enable long‐term, high‐fidelity electrophysiological (EP) signal monitoring. Its patterning capability further facilitates the fabrication of wearable and multi‐channel bioelectronic devices.
Anni Sun, Tenglong Luo, Huanxin Su, Zhengyan He, Fuchun Nan, Shuo Wang, Yu Wang, Yuanhao Wu, Lingyun Wang, Jie Zhang, William W. Yu   +10 more
wiley   +1 more source

Evolutionary constraints and regulatory plasticity shape host specialization in the <i>Magnaporthe oryzae</i> species complex. [PDF]

Virulence
Hera MHR, Wu Q, Jibril SM, Li C, Wang Y.
europepmc   +1 more source

Classified Comparison and Cause Analysis of the Characteristics of Co‐Disabilities Among Older Adults With Physical Disability in China

Health Care Science, EarlyView.
This study used prevalence comparisons and binary logistic regression to analyze the data from the First and Second China National Sample Survey on Disability conducted in 1987 and 2006, respectively. Co‐disability patterns among older adults with physical disability in China were examined, and the associations of other disability types with both the ...
Yiran Wang, Xiaodong Zhang, Lu Tan, Chenyu Yan, Xiaoqian Yan, Wenwen Liu, Tianran Wang, Sijiu Wang, Wannian Liang   +8 more
wiley   +1 more source

Sequence‐identical microbial genomes with disparate taxonomy: A large‐scale redundancy analysis in NCBI genome database

iMetaOmics, EarlyView.
Public microbial genome repositories (such as NCBI) contain thousands of sequence‐identical genome assemblies assigned to different taxonomic lineages, potentially inflating microbial diversity and introducing bias into comparative genomics, metagenomics, and pathogen surveillance.
Niharika Saraf, Gaurav Sharma
wiley   +1 more source

An LRR-truncated NLR natural variant confers dual resistance to drought and blast in rice. [PDF]

Nat Commun
Tu H, Ye Y, Wang H, Li S, Feng Z, Feng X, Liu Q, Li X, Ye T, Zhang Y, Hu D, Yan Y, Chen Y, Xing Y, Hu H, Dong F, Lai X, Xie K, Xiong H, Xiong L.   +19 more
europepmc   +1 more source

Multi‐omics reveals gastrointestinal metabolic disorder‐induced diarrhea in postpartum dairy cows

iMetaOmics, EarlyView.
Nutritional diarrhea is a pervasive, costly challenge in dairy production. Using integrated metagenomic and metabolomic profiling, we identified coordinated microbial and metabolic alterations across the rumen, hindgut, and serum. In the rumen, enrichment of Prevotella sp.
Weixuan Tang, Yangyi Hao, Jiawei Zhang, Yajing Wang, Zhijun Cao, Hongjian Yang, Wei Wang, Shengli Li   +7 more
wiley   +1 more source