Results 181 to 190 of about 80,415 (249)

Precision Medicine in Neurodegeneration with Brain Iron Accumulation (NBIA) Disorders: An Update on Emerging Treatments

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider, Divyani Garg, Vassilena Iankova, Thomas Klopstock   +3 more
wiley   +1 more source

Resistance architecture and breeding implications of blast and bacterial blight resistance genes in core WDR parents. [PDF]

BMC Plant Biol
Miao Z, Chen J, Kong D, Chen J, Li Z, Yu X, Xia H, Luo L, Liu Y.   +8 more
europepmc   +1 more source

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood, Jacinta R. Macdonald, Christian Anzenhofer, Tina S. Skinner‐Adams, Robert C. Reid, Thomas Kurz, David P. Fairlie, Katherine T. Andrews   +7 more
wiley   +1 more source

BUI1 coordinates actin cytoskeleton remodeling and ROS homeostasis to confer broad-spectrum disease resistance in rice. [PDF]

Stress Biol
Lin H, Cui K, Wang J, Jin Y, Zhang X, Lu Y, Wu X, Zhang L, Liu S, Liu J, Li Q, Deng Y, Yang W, He Z, Gao M.   +14 more
europepmc   +1 more source

The epigenetic landscape of plant defense: Unlocking nature's toolkit for new plant protection

New Plant Protection, EarlyView.
This review examines how epigenetic mechanisms regulate plant immune gene activation, repression, and priming, then links these natural regulatory layers to emerging epigenetic editing, discussing their potential for precise, heritable crop protection and the challenges.
Xuexia Liu, Zhenhui Zhong
wiley   +1 more source

Interplanetary frontiers: terraforming from an invasion science perspective

Oikos, EarlyView.
The pursuit of a multi‐planetary existence represents one of humanity's greatest frontiers. If applied justly, it offers an opportunity to extend its civilization's lifespan amid escalating sustainability crises on Earth. One approach increasingly gaining traction is terraforming, a hitherto theoretical ecological and evolutionary experiment revolving ...
Teun Everts, Ronaldo Sousa, Phillip J. Haubrock   +2 more
wiley   +1 more source

Combining blast resistance and high yield in F₁ aromatic rice through classical hybrid breeding. [PDF]

Sci Rep
Rashid MM, Rahman MM, Rashid MM, Arifuzzaman M, Majumder DAN, Hasan MM, Howlader NC, Soufan W, Sabagh AE, Islam MS.   +9 more
europepmc   +1 more source

Integrating and assessing metacommunity drivers of ecosystem function and resilience in benthic algal systems

Oikos, EarlyView.
Understanding the scales and mechanisms by which species composition interacts with ecosystem functions is critical for forecasting the effects of environmental perturbations on ecosystem services. However, the linkages between what regulates the ecosystem functions of dispersal‐capable networks of communities (metacommunities) and what regulates a ...
Thomas P. Shannon, Evelyn E. Gaiser
wiley   +1 more source

Nonstationarity in wildlife disease dynamics: insights from the prairie dog–plague system

Oikos, EarlyView.
Ecological relationships often vary in strength and direction across ecosystems, a pattern that has become increasingly evident as ecology expands to broader spatial and temporal scales. Although such nonstationarity – the changing effect of predictor variables across spatiotemporal contexts – is widely acknowledged in ecological research, it has ...
Gabriel M. Barrile, Joshua F. Layfield, David J. Augustine, Lauren M. Porensky, Courtney J. Duchardt, Imtiaz Rangwala, Ana D. Davidson   +6 more
wiley   +1 more source

A lightweight RPB-YOLO11-based detector improves mobile phenotyping of rice panicle blast. [PDF]

Front Plant Sci
Yang X, Zhao X, Xu C, Hu J, Xu L, Chi J, Zhang N, Wang X, Liu L, Liu B, Tang L, Cao W, Zhu Y, Feng Z, Xiao L.   +14 more
europepmc   +1 more source