Intraoperative Optical Coherence Tomography-Guided Bleb-sparing Epithelial Exchange: A Modified Approach [PDF]
Journal of Ophthalmic & Vision Research, 2021 With the advent of newer technologies, real-time anterior segment optical coherence tomography (OCT) integrated with the operating microscope has become possible.
Dewang Angmo +2 more
doaj +4 more sources
The size, shape, and dynamics of cellular blebs [PDF]
, 2012 A cellular bleb grows when a portion of the cell membrane detaches from the underlying cortex under the influence of a cytoplasmic pressure. We develop a quantitative model for the growth and dynamics of these objects in a simple two-dimensional setting.
Chiam, Keng-Hwee +2 more
arxiv +3 more sources
Novel approaches to model effects of subconjunctival blebs on flow pressure to improve clinical grading systems after glaucoma drainage surgery. [PDF]
PLoS ONE, 2019 Clinical grading systems following glaucoma filtration surgery do not include any effects of the bleb on the intra-ocular pressure and are relatively subjective, therefore carrying the risk of inter and/or intra-observer variability.
Yann Bouremel +4 more
doaj +2 more sources
A PDE model for bleb formation and interaction with linker proteins [PDF]
arXiv, 2019 The aim of this paper is to further develop mathematical models for bleb formation in cells, including cell-membrane interactions with linker proteins. This leads to nonlinear reaction-diffusion equations on a surface coupled to fluid dynamics in the bulk.
Burger, Martin +2 more
arxiv +5 more sources
Computer Simulation of Cytoskeleton-Induced Blebbing in Lipid Membranes [PDF]
, 2011 Blebs are balloon-shaped membrane protrusions that form during many physiological processes. Using computer simulation of a particle-based model for self-assembled lipid bilayers coupled to an elastic meshwork, we investigated the phase behavior and kinetics of blebbing.
Harvey, Cameron W. +4 more
arxiv +3 more sources
Volume changes during active shape fluctuations in cells [PDF]
, 2015 Cells modify their volume in response to changes in osmotic pressure but it is usually assumed that other active shape variations do not involve significant volume fluctuations. Here we report experiments demonstrating that water transport in and out of the cell is needed for the formation of blebs, commonly observed protrusions in the plasma membrane ...
Kardash, Elena +5 more
arxiv +5 more sources
The impact of conjunctival flap method and drainage cannula diameter on bleb survival in the rabbit model. [PDF]
PLoS ONE, 2018 To examine the effect of cannula diameter and conjunctival flap method on bleb survival in rabbits undergoing cannula-based glaucoma filtration surgery (GFS).Twelve New Zealand White rabbits underwent GFS in both eyes.
Cooper D Rodgers +8 more
doaj +6 more sources
Decreased DNA density is a better indicator of a nuclear bleb than lamin B loss. [PDF]
J Cell SciNuclear blebs are herniations of the nucleus that occur in diseased nuclei and cause nuclear rupture leading to cellular dysfunction. Chromatin and lamins are two of the major structural components of the nucleus that maintain its shape and function, but
Bunner S +26 more
europepmc +3 more sources
Confocal Microscopy of Filtering Blebs after Trabeculectomy [PDF]
Folia Medica, 2021 Introduction: Filtration surgery is the most effective method of lowering intraocular pressure (IOP) in patients with insufficient medical control. It consists in facilitating the drainage of the intraocular fluid (IOF) from the anterior chamber to the ...
Ralitsa D. Kermedchieva +4 more
doaj +3 more sources