Results 151 to 160 of about 17,542 (300)

Chronic optogenetic stimulation of dentate gyrus granule cells in mouse organotypic slice cultures synaptically drives mossy cell degeneration

open access: yesEpilepsia, EarlyView.
Abstract Objective Degeneration of hilar mossy cells in the dentate gyrus is an important hallmark of hippocampal sclerosis and is often observed in patients with temporal lobe epilepsy. To understand the pathogenesis of hippocampal sclerosis and develop novel neuroprotective treatments, it is critical to determine the mechanistic processes of mossy ...
Carolin Christina Koretz   +5 more
wiley   +1 more source

Computed tomography of the equine temporohyoid joint: Association between imaging changes and potential risk factors

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Temporohyoid osteoarthropathy (THO) is characterised by bone proliferation and cartilage ossification caused by infectious and degenerative conditions, amongst others. Objectives To describe the variable appearance of the temporohyoid joint (THJ) on computed tomography (CT) and investigate associations between CT changes and ...
Rupert F. Dash   +3 more
wiley   +1 more source

Extracellular ATP Causes ROCK I-dependent Bleb Formation in P2X7-transfected HEK293 Cells [PDF]

open access: green, 2003
Anna Morelli   +9 more
openalex   +1 more source

Cutaneous Side Effects of PD‐1 Inhibitors: A Single‐Center Retrospective Study

open access: yesInternational Journal of Dermatology, EarlyView.
ABSTRACT Background The introduction of immune checkpoint inhibitors (ICIs) opened a new era in cancer immunotherapy. In particular, PD‐1 inhibitors have shown remarkable efficacy in various cancers, most notably melanoma. However, the widespread use of immune checkpoint inhibitors comes with the challenge of immune‐related adverse events (irAEs), with
Melánia Pozsgai   +5 more
wiley   +1 more source

Incidence of bleb-associated endophthalmitis in the United States

open access: yesClinical Ophthalmology, 2015
Kamyar Vaziri,1 Krishna Kishor,1 Stephen G Schwartz,1 Arindel S Maharaj,1 Darius M Moshfeghi,2 Andrew A Moshfeghi,3 Harry W Flynn Jr1 1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL ...
Vaziri K   +6 more
doaj  

A Cautionary Tale About Not ‘Joining the Dots’ to Infer Anticlockwise P$$ P $$‐T$$ T $$ Paths

open access: yesJournal of Metamorphic Geology, EarlyView.
ABSTRACT Uncertainty surrounds the cause and interpretation of anticlockwise pressure‐temperature (P$$ P $$–T$$ T $$) paths in metamorphic terranes. Here, we focus on the viability of a commonly proposed mechanism—magmatic heat transfer during thickening—using a case study of the Roineabhal terrane in Scotland, where such an anticlockwise P$$ P $$–T ...
Owen Weller, Joseph Benson, Alex Copley
wiley   +1 more source

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