Results 81 to 90 of about 17,542 (300)
Early life functional transitions impact craniofacial morphology in osteogenesis imperfecta
Abstract Early life behaviors have a profound role in shaping adult craniofacial morphology. During early life, all mammals undergo the dynamic transition from suckling to mastication, a period coinciding with rapid cranial biomineralization. Osteogenesis imperfecta (OI), a genetic disorder that impacts the production of type I collagen, disrupts ...
Courtney A. Miller+2 more
wiley +1 more source
Voltage-gated channel mechanosensitivity: Fact or Friction?
The heart is a continually active pulsatile fluid pump that generates forces by precisely timed and spaced engagement of contractile nano-machinery. This pump largely generates its own control signals, the most crucial of which involve precisely timed ...
Catherine E Morris
doaj +1 more source
Abstract Measurement error (ME) in geometric morphometrics has been the subject of countless articles, but none specific to the effect of time lags on landmark digitization error. Yet, especially for visiting scientists working on museum collections, it is not uncommon to collect data in multiple rounds, with interruptions of weeks or years. To explore
Andrea Cardini
wiley +1 more source
Factors influencing the filtration-bleb volume after Ex-PRESS® surgery
Naoki Tojo, Atsushi Hayashi, Mitsuya Otsuka Department of Ophthalmology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan Purpose: The aim of this study was to investigate the factors influencing the volume of the ...
Tojo N, Hayashi A, Otsuka M
doaj
Cell shape changes underlie animal development, physiology, and disease. The cell surface is mechanosensitive to the microenvironment and cytoskeleton activities, which generate plasma membrane topographies recognized and affected by Arp2/3 actin network induction pathways to remodel cell shape during immune cell migration, neural progenitor cell ...
Tony J. C. Harris
wiley +1 more source
Abstract Background Bacterial meningitis (BM) and meningoencephalitis (BMEM) are associated with high case fatality rates and neurologic sequelae in people, but limited data exists on outcome in dogs. Hypothesis/Objectives To report the clinicopathologic features, treatment and outcome of BM/BMEM in dogs, with a focus on clinical presentation, relapse ...
Faye Rawson+5 more
wiley +1 more source
Analysis of a model microswimmer with applications to blebbing cells and mini-robots [PDF]
Recent research has shown that motile cells can adapt their mode of propulsion depending on the environment in which they find themselves. One mode is swimming by blebbing or other shape changes, and in this paper we analyze a class of models for movement of cells by blebbing and of nano- robots in a viscous fluid at low Reynolds number.
arxiv
Unjamming Transition as a Paradigm for Biomechanical Control of Cancer Metastasis
ABSTRACT Tumor metastasis is a complex phenomenon that poses significant challenges to current cancer therapeutics. While the biochemical signaling involved in promoting motile phenotypes is well understood, the role of biomechanical interactions has recently begun to be incorporated into models of tumor cell migration.
Grace Cai+2 more
wiley +1 more source
The article describes modern approaches for controlling wound healing after fistulizing glaucoma surgery. The review recounts international experience of steroidal and nonsteroidal anti-inflammatory drug and their efficacy research study ...
S. Yu. Petrov
doaj +1 more source
Abstract Due to the limited regenerative capacity in adult mammals, the loss of vestibular hair cells (HCs) leads to balance disorders. In this study, we chronologically reprogrammed adult vestibular supporting cells (SCs) via bimodal regulation of Notch signaling, mimicking dynamic changes in Notch signaling during inner ear development. We found that
Shan Zeng+5 more
wiley +1 more source