Results 101 to 110 of about 905,182 (316)

Factor X and combined factor VIIa/factor X augment coagulation potential in a plasma model of antithrombin-reduced hemophilia

Research and Practice in Thrombosis and Haemostasis
Background: Plasma-derived (pd) factor (F)VIIa/FX products are available for the hemostatic management of people with hemophilia with inhibitors in Japan. We have previously reported that FX alone augments emicizumab-driven hemostasis.
Shigeharu Oh, Yuto Nakajima, Eisuke Takami, Hirotoshi Nakano, Keiji Nogami   +4 more
doaj   +1 more source

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

Arthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos, William Daniel Soulsby III, Emily von Scheven   +2 more
wiley   +1 more source

Expert opinion on bleeding risk from invasive procedures in cirrhosis

BACKGROUND & AIMS: Despite several recent international guidelines, no consensus exists on the bleeding risk nor haemostatic parameter thresholds that define the safety of invasive procedures in patients with cirrhosis.
Riescher-Tuczkiewicz, A, Bleeding, in liver diseases investigators, Rautou, P-E, Kamath, PS, Bleeding, in liver diseases investigators†, Caldwell, SH, Villa, E   +6 more
core   +1 more source

Early pregnancy bleeding

, 2016
Background: Twenty to forty per cent of pregnant women will experience bleeding during the first trimester. Initial presentation is usually to the general practitioner. Complications of miscarriage, including threatened miscarriage and ectopic pregnancy,
Breeze, Carol
core  

Corticosteroids and risk of gastrointestinal bleeding: a systematic review and meta-analysis

, 2014
Objective To assess whether corticosteroids are associated with increased risk of gastrointestinal bleeding or perforation. Design Systematic review and meta-analysis of randomised, double-blind, controlled trials comparing a corticosteroid to placebo ...
Klemp, Marianne, Narum, Sigrid, Westergren, Tone   +2 more
core   +1 more source

Age-related and disease-specific changes in B-cell profiles in older adults with immune thrombocytopenia

Frontiers in Immunology
IntroductionImmune thrombocytopenia is an autoimmune bleeding disorder that is more prevalent among older adults. Ageing itself reduces B-cell counts, a change also observed in patients with ITP.
E. Monzón Manzano, C. Herrero Carrasco, P. Acuña, L. del Pino Molina, E. G. Arias-Salgado, A. Mendoza, R. Kapur, L. Porcelijn, M. Martín Salces, M. I. Rivas Pollmar, E. López-Granados, E. López-Granados, V. Jiménez Yuste, V. Jiménez Yuste, M. Gasior Kabat, R. Ramírez Martín, R. Ramírez Martín, N. Butta, M. T. Álvarez Román, M. T. Álvarez Román   +19 more
doaj   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Vaginal progesterone on the prevention of preterm birth and neonatal complications in high risk women: A randomized placebo-controlled double-blind study

Iranian Journal of Reproductive Medicine, 2016
Background: Preterm birth is the major cause of neonatal mortality and morbidity. Objective: The aim of this study was to evaluate the effect of prophylactic vaginal progesterone on decreasing preterm birth rate and neonatal complications in a high-risk
Azam Azargoon, Raheb Ghorbani, Fereshteh Aslebahar   +2 more
doaj  

To P or not to P. That is the wrong question.

Bleeding, Thrombosis and Vascular Biology
A few years ago, an article in the first issue of Bleeding, Thrombosis and Vascular Biology, argued that biomedical research should move beyond the mechanical use of the p-value. That message was not new, but it was timely. It remains timely today.
Augusto Di Castelnuovo, Giovanni de Gaetano   +1 more
doaj   +1 more source

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source