Results 151 to 160 of about 978,185 (305)

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Etiology-Specific Nomograms for Predicting First Variceal Bleeding in Decompensated HBV- and HCV-Related Cirrhosis. [PDF]

Int J Gen Med
Du M, Li T, Li H, Zhang X, Xiao B, Zhen M, Li Y, Ouyang Y.   +7 more
europepmc   +1 more source

To bleed or not to bleed. Is that the question? [PDF]

British Journal of Clinical Pharmacology, 2011
openaire   +2 more sources

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

Advanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian, Xu Wang, Alexis Pacheco Benitez, Erick Guerrero, Yaou Duan, Jingwen Wei, Lukas Farbiak, Daniel J. Siegwart   +7 more
wiley   +1 more source

Lower eGFR is independently associated with embolization‑requiring severe bleeding after percutaneous renal biopsy: a matched case-control study with dose-respons e analysis. [PDF]

Ren Fail
Xu Y, Huang W, Wu X, Lv H, Zhang Q, Lei W.   +5 more
europepmc   +1 more source

Fast Hydrogel Micro‐Actuators Driven by Electric Fields

Advanced Materials, EarlyView.
We report the fabrication of chemically programmable electroactuating microstructures through the first integration of two‐photon polymerization with electrically actuated gelatin methacrylate‐based hydrogels. By tailoring the charge of the polymer network, we demonstrate programmable polarity‐dependent bending, enabling microstructures that ...
Annaël Sort‐Montenegro, Jason M. Delente, Žiga Roblek, Yekaterina Tskhe, Luke Dowling, Colm Delaney, Larisa Florea   +6 more
wiley   +1 more source

Withholding Oral Anticoagulation at Discharge and Post-Discharge Stroke and Bleeding Vulnerability in a Predominantly Older Cohort Hospitalized With Acute Heart Failure and Atrial Fibrillation. [PDF]

Geriatr Gerontol Int
Yamamoto J, Nakamura K, Hayama H, Enomoto Y, Yamamoto M, Hara H, Hara H, Hiroi Y.   +7 more
europepmc   +1 more source

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

Minimizing bleeding risk in patients receiving direct oral anticoagulants for stroke prevention

, 2016
Jeffrey Steven Habert Department of Family and Community Medicine, University of Toronto, Toronto, ON, Canada Abstract: Many primary care physicians are wary about using direct oral anticoagulants (DOACs) in patients with nonvalvular atrial fibrillation (
Habert JS
core  

CytoSorb Application for Successful Control of Life-Threatening Gastrointestinal Bleeding Following Rivaroxaban Administration. [PDF]

Am J Case Rep
Raeva L, Petrov M, Cholakov M, Taha A, Petrov A, Handzhiev S.   +5 more
europepmc   +1 more source