Results 241 to 250 of about 978,185 (305)

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

Advanced Science, EarlyView.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He, Guodong Zhao, Yun Hu, Wenya Bai, Hao Tan, Shuai Yuan, Sihan Yang, Ye Zhu, Xiaohui Xu, Leilei Zheng   +9 more
wiley   +1 more source

Splenic Artery Embolization, A Therapy that Can be Life-Saving for Small Bowel Variceal Bleeding. [PDF]

Eur J Case Rep Intern Med
Radwan R, Ghantous M, Salem J, Khoury J, Geagea A, Chidiac K.   +5 more
europepmc   +1 more source

Targeted Degradation of STING by a Neutrophil Membrane‐Coated Nanoplatform Suppresses Microglial Pyroptosis After Subarachnoid Hemorrhage

Advanced Science, EarlyView.
MG1@NM‐Px serves as a microglia‐targeted STING‐degrading nanoplatform for subarachnoid hemorrhage. Following systemic administration, it crosses the blood–brain barrier and accumulates in activated microglia. STP1‐mediated STING ubiquitination and degradation suppress MAPK/inflammasome signaling, GSDME‐mediated pyroptosis, and IL‐1β release, revealing ...
Ruotian Zhang, Kaikun Yuan, Haoyu Zou, Hanfeng Qin, Jiale Liu, Jianda Sun, Feifan Zhang, Yuankui Wang, Tong Wang, Jiaxing Dai, Chunxu Li, Yichi Chen, Yingfeng Tu, Huaizhang Shi   +13 more
wiley   +1 more source

Post-Endoscopic Retrograde Cholangiopancreatography Bleeding After Endoscopic Stone Removal in Dialysis Patients: A Multicenter Retrospective Study. [PDF]

DEN Open
Nishimura M, Miwa H, Kaneko T, Kazuki E, Ritsuko O, Yuichi S, Hiromi T, Yoshimasa S, Goda Y, Funaoka A, Doba N, Irie K, Miura Y, Ishii T, Kondo M, Sugimori K, Maeda S.   +16 more
europepmc   +1 more source

Small-caliber cap-assisted identification of an exposed vessel and direct clipping for colonic diverticular bleeding. [PDF]

Endoscopy
Doba N, Someya M, Goto K, Yonamine R, Abe S, Maeda S.   +5 more
europepmc   +1 more source

Anticoagulation in Advanced Chronic Kidney Disease: Navigating Uncertainty. [PDF]

Turk J Haematol
Velioğlu A.
europepmc   +1 more source

Transition From Pulmonary to Gastrointestinal Hemorrhage: A Rare Case of Hematemesis in an Adolescent With Chronic Pulmonary Hypertension and Valvular Regurgitation. [PDF]

Clin Case Rep
Ashraf B, Hussain MU, Zahid A, Sohail F, Shoukat SEA, Yattassaye M, Ashraf N.   +6 more
europepmc   +1 more source

Entero-Appendiceal Fistula Presenting with Overt Gastrointestinal Bleeding: A Case Report. [PDF]

Surg Case Rep
Sato S, Munechika T, Nomaru R, Shiokawa K, Takeshita I, Sahara K, Kuno N, Matsumoto Y, Nagata K, Nagano H, Takahashi H, Yoshimatsu G, Hasegawa S.   +12 more
europepmc   +1 more source

"Left Atrial Appendage Closure Versus Medical Therapy in Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials". [PDF]

J Cardiovasc Electrophysiol
Al-Janabi AAH, Al-Shammari AS, Hageen AW, Al-Tuaama AZH, Al-Ibraheem AMT, Shahzaib M, Rathi D, Hamzah KA, Shweliya MA, Kurmasha YH, Wagdy M, Refaat MM.   +11 more
europepmc   +1 more source