Results 151 to 160 of about 54,705 (323)

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Clinical effect of the application of metronidazole gel on sub gingival scaling in periodontal patients

مجله دانشکده دندانپزشکی اصفهان, 2007
Introduction: Chemical plaque control methods are recommended as adjunctive to mechanical plaque control methods. The aim of this study was to determine and compare periodontal probing depth (PPD) and bleeding on probing (BOP) indices with and without ...
M Shahabuei, A Aslani, J Yaghini
doaj  

Efficacy of nonsurgical periodontal treatment on patients with periodontitis and type 2 diabetes mellitus: a systematic review and Bayesian network meta-analysis

Acta Odontologica Scandinavica
Objective: This study aimed to evaluate the effects of periodontal basic therapy combined with various adjunctive treatments on periodontal inflammation and glycemic control in patients with periodontitis and type 2 diabetes mellitus (T2DM) using ...
Xuejie Xie, Jun Xu, Yiming Li, Li Tang, Gulinuer Awuti   +4 more
doaj   +1 more source

Nanoscale Mapping of the Subcellular Glycosylation Landscape

Advanced Science, EarlyView.
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter, Steffen Sass, Mike Heilemann, Thomas Kuner, Maja Klevanski   +4 more
wiley   +1 more source

Assessment of Peri-Implant Tissue Health and Marginal Bone Loss in Immediate Versus Delayed Implant Placement

Journal of Pharmacy and Bioallied Sciences
Objectives: The ambition of this research is to gauge marginal bone loss (MBL) and peri-implant tissue health by comparing immediate and delayed implant implantation in a tertiary care setting.
Prashant A. Karni, Himaja Kasarla, Annesha Koinyaki Konwar, Irfa Junaid, Manawar Ahmad Mansoor, Sumedh Lone, Pooja Kadam   +6 more
doaj   +1 more source

Prevalence of bleeding on probing among patients at the periodontology clinic of Universitas Airlangga Dental Hospital [PDF]

, 2023
Eka Fitria, Muhammad Iqbal Jalaluddin, Adilia Suci Maulidia   +2 more
openalex   +1 more source

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

Advanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen, Jingke Li, Yangyang Liu, Li Li, Xin Deng, Yilin Sheng, Xianyu Zhu, Xiao Jiang, Wei Li, Xueli Cai, Qiming Sun, Hu Hu   +11 more
wiley   +1 more source

INTERLEUKIN-8 AND INTERLEUKIN-1Α LEVELS IN THE GINGIVAL CREVICULAR FLUID OF PERIODONTITIS PATIENTS AND THEIR CORRELATION WITH PERIODONTAL POCKET DEPTH AND BLEEDING ON PROBING

, 2022
Maheen Tariq, Wan Nazatul Shima Shahidan, Raja Azman Awang   +2 more
openalex   +2 more sources

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source

Expandable Nanocomposite Shape‐Memory Hemostat for the Treatment of Noncompressible Hemorrhage

Advanced Science, EarlyView.
A nanocomposite‐coated shape memory foam rapidly expands, accelerates clotting, and reduces blood loss in vivo. Its fast volumetric expansion and strong procoagulant activity make it a promising hemostat for treating deep, noncompressible hemorrhage.
Saptarshi Biswas, Sarah E. Miller, Shounak Roy, Jeevika Thazhaiselvam, Samantha Foster, Manivannan Sivaperuman Kalairaj, Sasha M. George, Yava Jones‐Hall, Staci J. Horn, Fred J. Clubb, Taylor H. Ware, Duncan J. Maitland, Akhilesh K. Gaharwar   +12 more
wiley   +1 more source