Results 61 to 70 of about 6,710 (240)

OXA1L deficiency causes mitochondrial myopathy via reactive oxygen species regulated nuclear factor kappa B signalling pathway

Clinical and Translational Medicine, Volume 15, Issue 6, June 2025.
OXA1L gene bi‐allelic variants cause mitochondrial myopathy. OXA1L deficiency results in combined mitochondrial respiratory chain defects and OXPHOS impairments. OXA1L deficiency leads to elevated ROS production, which may activate the NF‐κB signalling pathway, disturbing myogenic gene expression and triggering cell apoptosis. Abstract Background OXA1L
Yongkun Zhan, Qian Wang, Ya Wang, Yanjie Fan, Dan Yan, Xianlong Lin, Yaoting Chen, Tingting Hu, Nan Li, Weiqian Dai, Hezhi Fang, Yongguo Yu   +11 more
wiley   +1 more source

Unilateral Blepharoptosis From Renal Cell Carcinoma

Journal of Kidney Cancer and VHL, 2016
Blepharoptosis is the drooping or inferior displacement of the upper eyelid. Blepharoptosis can be either congenital or acquired. Tumour metastasis is one of the acquired causes of blepharoptosis.
Federico Greco, Lorenzo Sabatino, Francesco Sabatino, Manuele Casale, Carlo Cosimo Quattrocchi, Bruno Beomonte Zobel   +5 more
doaj   +1 more source

Observation of Safety and Efficacy of Botulinum Toxin Type A in the Treatment of Tear Troughs and Mild Yelid Bags

Journal of Cosmetic Dermatology, Volume 24, Issue 6, June 2025.
ABSTRACT Objective To evaluate the safety and efficacy of Botulinum Toxin Type A (BTX‐A) injection for the treatment of tear troughs. Method This study included patients with tear troughs rated as Grade 1–2 on the Barton Aesthetic Scale, who were treated between September 2023 and September 2024.
Siyuan Zhou, Homgtao Liu, Zhongjie Pan, Fuqiang Pan, Qian Liang, Houhuang Qiu, Bingliang Wu, Liming Zhang, Xiang Zhou   +8 more
wiley   +1 more source

Presentation and Outcomes of Localized Immunoglobulin Light Chain Amyloidosis: 14‐Year Experience of an Academic Center

Hematological Oncology, Volume 43, Issue 3, May 2025.
ABSTRACT Localized light chain amyloidosis (loc‐AL) is a rare disorder characterized by localized deposition of misfolded AL fibrils. There are limited data on patterns of disease presentation and long‐term outcomes. In this study, we retrospectively reviewed 146 patients with loc‐AL at our institution between January 1, 2010, and March 1, 2024.
Danai Dima, Utkarsh Goel, Fauzia Ullah, Beth Faiman, Diana Basali, Sandra Mazzoni, Louis S. Williams, Christy Samaras, Jason Valent, Faiz Anwer, Jack Khouri, Shahzad Raza   +11 more
wiley   +1 more source

Cerebellar Atrophy in Congenital Fibrosis of the Extraocular Muscles Type 1 [PDF]

, 2012
We described a family with a molecularly confirmed form of CFEOM1 and a late-onset cerebellar syndrome. Brain MRI showed vermis atrophy in two older family members, who also manifested gait impairment, whereas both neurological examination and ...
Alessandra Tessa, Carlo Casali, DE BERARDINIS, TERESA, Filippo Maria Santorelli, Francesca Piccolo, Francesco Pierelli, Giovanna Comanducci, Roberto Di Fabio, Umberto Sabatini   +8 more
core   +1 more source

Elephant skin and droopy lids: A rare case report of touraine-solente-gole syndrome

TNOA Journal of Ophthalmic Science and Research, 2021
Touraine-Solente-Gole syndrome which is also known as pachydermoperiostosis is a multisystem disorder that affects bone, skin including eyelids, gastrointestinal system, and endocrine system.
Rita Hepsi Rani, V Sweetha, Thendral Velmurugan   +2 more
doaj   +1 more source

Safety and patient satisfaction of abobotulinumtoxinA for aesthetic use. A systematic review [PDF]

, 2017
A systematic review of the published literature (from January 2000 to January 2016) to ascertain the safety of, and patient satisfaction with, the aesthetic use of abobotulinumtoxinA was conducted.
Cohen, Joel L, Scuderi, Nicolo'
core   +1 more source

Combination of Botulinum Toxin A and Hyaluronic Acid Improved Facial Pore Enlargement Caused by Acne

Journal of Cosmetic Dermatology, Volume 24, Issue 4, April 2025.
ABSTRACT Background Acne often leads to enlarged pores on the facial skin, seriously affecting the patient's appearance. Topical and oral medications have poor efficacy in some cases of severe pore enlargement. Objective This study aimed to explore the clinical efficacy and safety of botulinum toxin A combined with hyaluronic acid in improving facial ...
Rongli Yang, Yiyang Bai, Chang Liu, Jintian Luo, Yajie Yang, Shaoli Cheng, Muyan Zou, Xin Mu   +7 more
wiley   +1 more source

Comparative study between local and general anesthesia in the management of sever blepharoptosis by use of straight needle threading technique as frontalis suspension [PDF]

The Medical Journal of Basrah University, 2017
Aim: is to compare between the outcome and complications in the use of local and general anesthesia in the management of sever blepharoptosis by use of straight needle threading technique and silk suture as a frontalis suspension.
Amer S. Al Mansory
doaj   +1 more source

Surgical approach to limiting skin contracture following protractor myectomy for essential blepharospasm [PDF]

, 2017
Purpose: To report our experience with protractor myectomy in patients with benign essential blepharospasm who did not respond to serial botulinum toxin injection, and to describe intra- and postoperative techniques that limited skin contracture while
Clark, Jeremy, Lee, Hui Bae H., Moore, Nicholas A., Nunery, William R., Randolph, John, Sokol, Jason A.   +5 more
core   +1 more source