Results 231 to 240 of about 388,128 (288)

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Eco-benign phytochemically-functionalized Ag-core Fe-shell bimetallic nanoparticles for targeted antioxidant and anti-inflammatory drug delivery. [PDF]

BMC Chem
Iheme CI, Mogbonjubola MA, Iwuchukwu BK, Alisi PN, Nkwoada AU, Okpara CJ, Ibeh OO, Esonu CE, Ubah VCS, Chiegboka NA, Oguzie CK, Ujowundu CO.   +11 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Erratum: Education Research: Neurologic Education in Nurse Practitioner Programs. [PDF]

Neurol Educ
Swider K, Cook C, DiLibero J, Hall KE, Naclerio M, Gheihman G, Morse L, Busler A, Woods EO, Walsh M, Doughty CT, Harrison D.   +11 more
europepmc   +1 more source

Tiger, tiger burning bright:is tourism a blessing or a blight? [PDF]

, 2011
Susanna Curtin
openalex  

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Enhanced Multi-Model Machine Learning-Based Dementia Detection Using a Data Enrichment Framework: Leveraging the Blessing of Dimensionality. [PDF]

Bioengineering (Basel)
Yongcharoenchaiyasit K, Arwatchananukul S, Hristov G, Temdee P.   +3 more
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Common AAV gene therapy vectors show nonselective transduction of <i>ex vivo</i> human brain tissue. [PDF]

Mol Ther Methods Clin Dev
McGinnis JP, Ortiz-Guzman J, Guevara MC, Mallannagari S, Belfort BDW, Bao S, Srivastava S, Morkas M, Ji E, Addison A, Tantry EK, Chen S, Wang Y, Chen Z, Katlowitz KA, Lange JJ, Blessing MM, Mohila CA, Ljungberg MC, Aldave G, Jalali A, Patel A, Sheth SA, Weiner HL, Gopinath S, Rao G, Harmanci AS, Curry DJ, Arenkiel BR.   +28 more
europepmc   +1 more source

Bumper Harvests a Curse or a Blessing for Zambia: Lessons from the 2014/15 Maize Marketing Season.

, 2019
Antony Chapoto, Brian Chisanga, Auckland Kuteya, Stephen Kabwe   +3 more
openalex   +2 more sources