DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
The unscientific nature of the arguments of "Restorative Reproductive Medicine" and why we need to understand them. [PDF]
Paulson RJ.
europepmc +1 more source
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
A lived experience transformation of mental illness to mental health: Inspiring a movement of hope. [PDF]
McLure J.
europepmc +1 more source
Age‐Related Changes in Myeloid Cells and Their Impact on Subcutaneous Melanoma Growth in Mice
Our findings reveal that age‐related changes in subcutaneous melanoma growth and immunotherapy response are context‐dependent. In models where tumor growth and treatment resistance increase with age, this effect is partly driven by enhanced immunosuppression from myeloperoxidase‐active Gr‐1⁺ myeloid cells.
Kaitlyn M. Landreth +7 more
wiley +1 more source
Student's feedback-seeking behavior: A blessing or burden for supervisors. [PDF]
Qadir I, Khan RA, Khalid M, Yasmeen R.
europepmc +1 more source
Where blessing and curse merge with life and death: Local beliefs in contemporary Lower Kuttanad
Thresy Vallikappen
openalex +1 more source
Early experience with resmetirom to treat metabolic dysfunction-associated steatohepatitis with fibrosis in a real-world setting. [PDF]
Ravela N +5 more
europepmc +1 more source
Sensitivity, Blessing and Doxology: Archival Practice as Spiritual Discipline
McGarvey Ice
openalex +1 more source

