Results 141 to 150 of about 2,961,150 (281)

Smartphone-Based Acoustic Sensing for Breathing and Heartbeat Detection via AoA Clustering in Indoor Environments. [PDF]

Sensors (Basel)
Vincent K, Khan I, Sun K, Shao Y, Liang Z, Ullah A, Gong T.   +6 more
europepmc   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Defect-Polarization Coupling in 3D-Graphene/β-Ga₂O₃ Heterostructures for Self-Powered and Multifunctional Solar-Blind Ultraviolet Photodetection. [PDF]

Small
Zhu F, Wang Y, Li Z, Cao G, Ma H, Qian K, Li S, Zhang J, Lian S, Zheng L, He P, Zhao Y, Gao M, Xu W, Wang X, Wang G.   +15 more
europepmc   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Transformer-Based Nonlinear Blind Source Separation for Anti-Jamming in DSSS Satellite Communications. [PDF]

Sensors (Basel)
Sun X, Li C, Li J, Su Q.
europepmc   +1 more source

An Efficient Detection Platform Based on Mesoporous Au@Cr₂O₃ Particles with Schwarz P Surface for Precise Periodontitis Metabolite Profiling. [PDF]

Adv Sci (Weinh)
A non‐invasive periodontitis diagnosis platform was developed using Au nanoparticles‐decorated mesoporous Cr2O3 (Au@mCr2O3) particles with Schwarz P surface as matrix for saliva metabolic fingerprinting (SMFs) analysis via MALDI‐MS. With the assistance of machine learning of SMFs, this platform enables efficient diagnosis and the screening of potential
Sun Y, Wang Y, Shi F, Xie W, Zhang Y, Zhang H, Deng C, Wu L, Chen M, Deng Y.   +9 more
europepmc   +2 more sources

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

A Symmetric ICA-Based CDMA Receiver for Dense IoT-Enabled Healthcare Monitoring Systems. [PDF]

Sensors (Basel)
Anjum MI, Waqas A, Saleem A.
europepmc   +1 more source

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source

Frequency-Domain Second-Order Decorrelation with Compact Time-Domain Regularization for Convolutive Underwater Acoustic Source Separation. [PDF]

Sensors (Basel)
Cao H, Yang T, He Q, Yiu KC.
europepmc   +1 more source