Results 41 to 50 of about 195,151 (333)

Single-Channel Blind Image Separation Based on Transformer-Guided GAN

Sensors, 2023
Blind source separation (BSS) has been a great challenge in the field of signal processing due to the unknown distribution of the source signal and the mixing matrix.
Yaya Su, Dongli Jia, Yankun Shen, Lin Wang   +3 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

On a Real-Time Blind Signal Separation Noise Reduction System

International Journal of Reconfigurable Computing, 2018
Blind signal separation has been studied extensively in order to tackle the cocktail party problem. It explores spatial diversity of the received mixtures of sources by different sensors. By using the kurtosis measure, it is possible to select the source
Ka Fai Cedric Yiu, Siow Yong Low
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

A MLE-based blind signal separation method for time–frequency overlapped signal using neural network

EURASIP Journal on Advances in Signal Processing, 2022
The blind signal separation (BSS) algorithm obtains each original/source signal from the observed signal collected by the receiving antenna or sensor. Objective/loss/cost function and optimization method are two key parts of BSS algorithm.
Lihui Pang, Yilong Tang, Qingyi Tan, Yulang Liu, Bin Yang   +4 more
doaj   +1 more source

Sparse and Non-Negative BSS for Noisy Data

, 2013
Non-negative blind source separation (BSS) has raised interest in various fields of research, as testified by the wide literature on the topic of non-negative matrix factorization (NMF). In this context, it is fundamental that the sources to be estimated
Bobin, Jérôme, Larue, Anthony, Rapin, Jérémy, Starck, Jean-Luc   +3 more
core   +3 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Study on weak sound signal separation and pattern recognition under strong background noise in marine engineering

Journal of Low Frequency Noise, Vibration and Active Control
The extraction of weak acoustic signals under strong background noise is of great significance in the applications of target identification and localization.
Song Liu, Jiantong Gao, Huayu Zhou, Kang Yang, Panpan Liu, Yifan Du   +5 more
doaj   +1 more source

A Blind Source Separation Method Based on Bounded Component Analysis Optimized by the Improved Beetle Antennae Search

Sensors, 2023
Currently, the widely used blind source separation algorithm is typically associated with issues such as a sluggish rate of convergence and unstable accuracy, and it is mostly suitable for the separation of independent source signals.
Mingyang Tang, Yafeng Wu
doaj   +1 more source