Results 51 to 60 of about 451,315 (310)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Blind Source Separation with Compressively Sensed Linear Mixtures

open access: yes, 2011
This work studies the problem of simultaneously separating and reconstructing signals from compressively sensed linear mixtures. We assume that all source signals share a common sparse representation basis.
Kleinsteuber, Martin, Shen, Hao
core   +1 more source

Contribution of Statistical Tests to Sparseness-Based Blind Source Separation [PDF]

open access: yes, 2012
International audienceWe address the problem of blind source separation in the underdetermined mixture case. Two statistical tests are proposed to reduce the number of empirical parameters involved in standard sparseness-based underdetermined blind ...
Aissa El Bey, Abdeldjalil   +2 more
core   +2 more sources

Power Systems Topology and State Estimation by Graph Blind Source Separation [PDF]

open access: yesIEEE Transactions on Signal Processing, 2018
In this paper, we consider the problem of blind estimation of states and topology (BEST) in power systems. We use the linearized dc model of real power measurements with unknown voltage phases (i.e., states) and an unknown admittance matrix (i.e ...
Sivan Grotas   +3 more
semanticscholar   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

A new blind source separation framework for signal analysis and artifact rejection in functional Near-Infrared Spectroscopy

open access: yesNeuroImage, 2019
In the analysis of functional Near-Infrared Spectroscopy (fNIRS) signals from real-world scenarios, artifact rejection is essential. However, currently there exists no gold-standard. Although a plenitude of methodological approaches implicitly assume the
A. Lühmann   +3 more
semanticscholar   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Extracting individual contributions from their mixture: a blind source separation approach, with examples from space and laboratory plasmas

open access: yes, 2010
Multipoint or multichannel observations in plasmas can frequently be modelled as an instantaneous mixture of contributions (waves, emissions, ...) of different origins.
Amblard   +24 more
core   +4 more sources

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