Results 81 to 90 of about 42,664 (162)
Advanced Healthcare Materials, Volume 15, Issue 19, 22 May 2026.A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen +9 more
wiley +1 more source
Advanced Materials, Volume 38, Issue 26, 8 May 2026.A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade +19 more
wiley +1 more source
Development and validation of MethylCog, a blood DNA methylation proxy for cognition
Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.Abstract INTRODUCTION Heterogeneity in cognitive ability increases with age and predicts mild cognitive impairment (MCI) and dementia, but scalable blood‐based biomarkers are lacking. We developed and validated MethylCog, a parsimonious DNA methylation (DNAm) marker of general cognitive ability (g).
Deirdre M. O'Shea +9 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.FGF10‐FGFR2 signaling is progressively impaired during liver fibrosis. FGF10 restoration protects hepatocytes from inflammatory and apoptotic injury. Hepatocyte FGFR2 mediates FGF10‐driven suppression of fibrogenic remodeling through the GSK3β/NF‐κB axis.
Xuanxin Yang +20 more
wiley +1 more source
rTCT: Rodent Triangle Completion Task to Facilitate Reverse Translational Study of Path Integration
Hippocampus, Volume 36, Issue 3, May 2026.ABSTRACT Path integration is navigation in the absence of environmental landmarks and is a primary cognitive mechanism underlying spatial memory. Path integration performance is primarily assessed in humans using the Triangle Completion Task (TCT). In humans, TCT has shown promise for the early diagnosis of Alzheimer's disease.
Stephen Duncan +13 more
wiley +1 more source
Small, Volume 22, Issue 26, 8 May 2026.Identified through multi‐stage selection process, a formulation combining γ‐oryzanol and DLin‐KC2‐DMA, termed as OryKL, demonstrates unique nano‐structural features, highly efficient mRNA transfection and functional integrity during long‐term storage, enables broad biodistribution and distinct cell tropism following intravenous administration with no ...
Pengkai Shi +12 more
wiley +1 more source
AI‐Enabled Imaging for Pathogen Detection Under Stress Conditions: A Systematic Review
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.ABSTRACT Advances in pathogen detection that incorporate artificial intelligence (AI) may capture microbial signals under challenging environmental conditions that traditional methods miss. This systematic review evaluates the application, performance, and methodological characteristics of AI‐enabled imaging for pathogen detection, including its impact
MeiLi Papa +3 more
wiley +1 more source
International Journal of Dental Hygiene, Volume 24, Issue 2, Page 278-306, May 2026.ABSTRACT Focused Question What is the association of periodontal disease (PerioD) and cardiovascular diseases (CVD/CVE) as reported in existing systematic reviews (SRs)? Methods MEDLINE‐PubMed and Cochrane‐CENTRAL databases were searched. Papers that primarily evaluate cardiovascular parameters of CVD and CVE in PerioD patients compared to non‐PerioD ...
Max G. P. Schoenmakers +4 more
wiley +1 more source
Journal of Anatomy, Volume 248, Issue 5, Page 719-738, May 2026.This study investigates human cortical bone remodeling space morphology and its relationship with age and sex using micro‐CT imaging. Remodeling space morphology exhibits great inter‐ and intraindividual variation. Its dimensions decrease with increasing age, but do not differ between sexes.
Xuan Wei +2 more
wiley +1 more source