Results 131 to 140 of about 375,956 (287)

Fumarate Hydratase Lactylation Exacerbates Traumatic Brain Injury Pathology via Mitochondrial Dysfunction and Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Tian et al. reveal that FH K112 lactylation is elevated after TBI, leading to fumarate accumulation, mitochondrial damage, mtDNA release and amplified neuroinflammation. AARS2 and SIRT3 act as the “writer” and “eraser” for FH K112 lactylation. The peptide Pep‐K112 targeting this site alleviates brain injury, highlighting a potential therapeutic target.
Yang Tian   +21 more
wiley   +1 more source

Postpartum cortical blindness.

open access: yesJournal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2008
A 30-years-old third gravida with previous normal pregnancies and an unremarkable prenatal course had an emergency lower segment caesarean section at a periphery hospital for failure of labour to progress. She developed bilateral cortical blindness immediately after recovery from anesthesia due to cerebral angiopathy shown by CT and MR scan as cortical
openaire   +1 more source

Palmitoyl Acyltransferase Zdhhc17 Promotes Functional Recovery After Spinal Cord Injury by Targeting the Nuclear Transport Factors Kpna2 and Ipo9

open access: yesAdvanced Science, EarlyView.
In this study, we demonstrate that Zdhhc17, acting as a PAT, suppresses neuronal apoptosis and promotes axon regeneration after injury, thereby enhancing functional recovery following SCI. In this context, Kpna2 and Ipo9 serve as novel palmitoylation substrates of Zdhhc17, whose palmitoylation prevents the injury‐induced degradation of their proteins ...
Meixuan Chen   +12 more
wiley   +1 more source

An unusual presentation of Moyamoya disease managed conservatively in a resource limited region: A case report. [PDF]

open access: yesRadiol Case Rep
Tabassum Z   +7 more
europepmc   +1 more source

Decoding the Neural Circuit Underlying Context‐Cue Association in Retrieval of Morphine Reward Memory

open access: yesAdvanced Science, EarlyView.
Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi   +8 more
wiley   +1 more source

Delayed reversible cortical blindness after spinal anesthesia with bupivacaine

open access: yesAnnals of Indian Academy of Neurology, 2022
Boby V Maramattom
doaj   +1 more source

Congenital blindness reduces myelination in human visual cortex. [PDF]

open access: yesSci Adv
Stroh AL   +7 more
europepmc   +1 more source

Prevent Blindness America : working to advance public health, vision and eye care in the U.S. [PDF]

open access: yes
A Summary Report of a Five-Year Cooperative Agreement with The Vision Health Initiative of the Centers for Disease Control and Prevention (2003\u20132008)pba_complete_508_final ...

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