Results 141 to 150 of about 624,004 (359)

Detection of Hard Exudates in Retinal Fundus Images using Deep Learning

open access: yes, 2018
Diabetic Retinopathy (DR) is a retinal disorder that affects the people having diabetes mellitus for a long time (20 years). DR is one of the main reasons for the preventable blindness all over the world. If not detected early the patient may progress to
Benzamin, Avula, Chakraborty, Chandan
core   +1 more source

A Novel Protein‐Polysaccharide Oral Nanoemulsion Targeting Activated Hepatic Stellate Cells to Enhance the Therapeutic Effect of Pirfenidone on Fibrosis After Transarterial Chemoembolization for Liver Cancer

open access: yesAdvanced Functional Materials, EarlyView.
Transarterial Chemoembolization (TACE) may aggravate liver fibrosis. In this study, a novel oral targeting nanoemulsion is fabricated to enhance the therapeutic effect of antifibrotic drug‐pirfenidone (PFD) on fibrosis after TACE. Studies have shown that PFD nanoemulsion can enhance the oral liver targeting effect of PFD, and effectively improve the ...
Zhimei Cheng   +12 more
wiley   +1 more source

Inequality and inequity in eye health

open access: yesCommunity Eye Health Journal, 2016
According to the 2010 Global Burden of Disease (GBD) study, the global prevalence of blindness (age-standardised) has declined from 0.60% in 1990 to 0.47% in 2010.
Johannes Trimmel
doaj  

Joule‐Assisted Nanotherapeutic Urethral Stent (JANUS) for Spatiotemporal Theragenerative Treatment of Urethral Strictures

open access: yesAdvanced Functional Materials, EarlyView.
Joule‐assisted nanotherapeutic urethral stent harnesses a smart, biodegradable magnesium stent to orchestrate spatiotemporal theragenerative therapy for urethral strictures. Magnetically induced Joule heating enables on‐demand drug release and bacterial ablation, while simultaneously guiding urothelial regeneration.
Yuhyun Na   +15 more
wiley   +1 more source

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

open access: yesAdvanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García   +23 more
wiley   +1 more source

KR-31378, a Potassium-Channel Opener, Induces the Protection of Retinal Ganglion Cells in Rat Retinal Ischemic Models

open access: yesJournal of Pharmacological Sciences, 2009
KR-31378 is a newly developed KATP-channel opener. To investigate the ability of KR-31378 to protect retinal ganglion cells (RGC), experiments were conducted using two retinal ischemia models.
Anho Choi   +4 more
doaj  

Designing Born-Accessible Courses in Data Science and Visualization: Challenges and Opportunities of a Remote Curriculum Taught by Blind Instructors to Blind Students [PDF]

open access: yesarXiv
While recent years have seen a growing interest in accessible visualization tools and techniques for blind people, little attention is paid to the learning opportunities and teaching strategies of data science and visualization tailored for blind individuals. Whereas the former focuses on the accessibility issues of data visualization tools, the latter
arxiv  

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