Results 51 to 60 of about 110,255 (263)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Convolutional cylinder-type block-circulant cycle codes [PDF]
Transactions on Combinatorics, 2013 In this paper, we consider a class of column-weight two quasi-cyclic low-density paritycheck codes in which the girth can be large enough, as an arbitrary multiple of 8. Then we devote a convolutional form to these codes, such that their generator matrix
Mohammad Gholami, Mehdi Samadieh
doaj
Finite Length Analysis of Low-Density Parity-Check Codes on Impulsive Noise Channels
IEEE Access, 2016 Low-density parity-check (LDPC) codes with very long block lengths are well known for their powerful error correction, but it is not always desirable to employ long codes in communication systems, where latency is a serious issue, such as voice and video
Zhen Mei +3 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Super-Orthogonal Block Codes with Multichannel Equalisation and OFDM in Frequency Selective Fading
EURASIP Journal on Wireless Communications and Networking, 2010 Super-orthogonal block codes in space-time domain (i.e., Super-orthogonal space-time trellis codes (SOSTTCs)) were initially designed for frequency nonselective (FNS) channels but in frequency selective (FS) channels these super-orthogonal block codes ...
O. Sokoya, B. T. Maharaj
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Performance Evaluation of Spatial Modulation and QOSTBC for MIMO Systems
EAI Endorsed Transactions on Mobile Communications and Applications, 2015 Multiple-input multiple-output (MIMO) systems require simplified architectures that can maximize design parameters without sacrificing system performance. Such architectures may be used in a transmitter or a receiver.
K.O.O. Anoh +5 more
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source