Results 161 to 170 of about 911,714 (247)

Kidney Fibrosis In Vitro and In Vivo Models: Path Toward Physiologically Relevant Humanized Models

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses kidney diseases with a focus on kidney fibrosis and the models currently used. It highlights the limitations of animal and 2D in vitro models in replicating human kidney anatomy and physiology. Consequently, there is a significant need for humanized 3D in vitro models, such as 3D cell aggregates, membranes and hydrogels, on‐chip ...
Gabriele Addario   +2 more
wiley   +1 more source

Advancing Chronic Wound Healing through Electrical Stimulation and Adipose‐Derived Stem Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Chronic cutaneous wounds represent significant challenges due to delayed healing and resistance to conventional treatments. This review explores the potential of combining adipose‐derived stem cells with electrical stimulation to enhance wound healing.
Qiuyue Peng   +5 more
wiley   +1 more source

Reward recalibrates rule representations in human amygdala and hippocampus intracranial recordings. [PDF]

open access: yesNat Commun
Manssuer L   +7 more
europepmc   +1 more source

Universal Hydrogel Carrier Enhances Bone Graft Success: Preclinical and Clinical Evaluation

open access: yesAdvanced Healthcare Materials, EarlyView.
TX hydrogel improves the delivery of different types of particulate bone grafts, maintaining them at the implantation sites, and resulting in favorable bone regenerative outcomes. Abstract Orthopedic, maxillofacial, and complex dentoalveolar bone grafting procedures that require donor‐site bone harvesting can be associated with post‐surgical ...
Dax Calder   +9 more
wiley   +1 more source

Viscoelastic HyA Hydrogel Promotes Recovery of Muscle Quality and Vascularization in a Murine Model of Delayed Rotator Cuff Repair

open access: yesAdvanced Healthcare Materials, EarlyView.
Rotator cuff tears, a common musculotendinous injury, often lead to permanent functional disability. A novel hyaluronic acid‐based hydrogel shows promise in promoting muscle regeneration after rotator cuff repair. The hydrogel reduces fibrosis, fatty infiltration, and muscle atrophy while supporting vascularization in a murine model.
Morgan R. Pfaff   +11 more
wiley   +1 more source

Principled neuromorphic reservoir computing. [PDF]

open access: yesNat Commun
Kleyko D   +5 more
europepmc   +1 more source

Unlocking the Gates: A Novel Diagnostic Molecule for Quantifying Efflux Levels in Gram‐Positive Bacteria

open access: yesAdvanced Healthcare Materials, EarlyView.
Efflux‐mediated resistance compromises antibiotic efficacy, yet rapid detection remains elusive. This study presents a novel phenazinium‐based diagnostic molecule for quantifying bacterial efflux levels in Gram‐positive pathogens. The optimized compound enables precise, real‐time efflux assessment using fluorescence and colorimetric techniques ...
Mrunal Patil   +15 more
wiley   +1 more source

Supramolecular Additive Screening to Engineer Microfibrous Rafts for Expansion of Pluripotent Stem Cells in Dynamic Suspension

open access: yesAdvanced Healthcare Materials, EarlyView.
Segmented PCL‐bisurea (BU) polymers and BU‐peptide conjugate additives assemble into fibrous superstructures at the nanoscale through a mix‐and‐matching strategy. Different bioactivities are incorporated through variation of peptide sequences. The resulting materials are screened for their effect on stem cell adhesion and pluripotency.
Johnick F. van Sprang   +6 more
wiley   +1 more source

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