Results 11 to 20 of about 76,394 (200)

Stability of the replica-symmetric saddle-point in general mean-field spin-glass models

, 2010
Within the replica approach to mean-field spin-glasses the transition from ergodic high-temperature behaviour to the glassy low-temperature phase is marked by the instability of the replica-symmetric saddle-point.
Andreas Engel, Bray A J, Cizeau P, Cizeau P, de Almeida J R L, Edwards S F, Engel A, Janzen K, Katharina Janzen, Mezard M, Mezard M, Monasson R, Monasson R, Mézard M, Parisi G, Pendry J B, Viana L, Weigt M, Weigt M, Weyl H, Wigner E   +20 more
core   +1 more source

Steiner t-designs for large t

, 2008
One of the most central and long-standing open questions in combinatorial design theory concerns the existence of Steiner t-designs for large values of t. Although in his classical 1987 paper, L.
A. Betten, A. Delandtsheer, D. Gorenstein, D. Livingstone, D. Pei, D.G. Higman, D.K. Ray-Chaudhuri, D.R. Hughes, D.R. Stinson, D.R. Stinson, F. Buekenhout, F. Buekenhout, G.-C. Rota, H. Lüneburg, H. Wielandt, J. Saxl, J. Tits, J.D. Dixon, J.H. Conway, L. Teirlinck, M. Hall Jr., M. Huber, M. Huber, M. Huber, M. Huber, M.W. Liebeck, M.W. Liebeck, N.D. Tuan, P. Dembowski, P. Kaski, P.J. Cameron, P.J. Cameron, P.J. Cameron, P.J. Cameron, P.J. Cameron, R.A. Fisher, R.E. Block, T.. Beth, W.C. Huffman, W.M. Kantor, W.M. Kantor   +40 more
core   +2 more sources

DBI analysis of generalised permutation branes [PDF]

, 2009
We investigate D-branes on the product GxG of two group manifolds described as Wess-Zumino-Novikov-Witten models. When the levels of the two groups coincide, it is well known that there exist permutation D-branes which are twisted by the automorphism ...
A Abouelsaood, A Giveon, A Recknagel, C Caviezel, CG Callan Jr, Cosimo Restuccia, ES Fradkin, G Sarkissian, G Sarkissian, I Brunner, JM Figueroa-O’Farrill, JM Maldacena, MR Gaberdiel, S Fredenhagen, S Fredenhagen, S Fredenhagen, S Förste, S Ribault, SK Ashok, Stefan Fredenhagen, T Bröcker, T Quella, V Braun   +22 more
core   +2 more sources

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Minimal generation of transitive permutation groups [PDF]

, 2018
It is proved in [21] that there is a constant $c$ such that each transitive permutation group of degree $d\ge 2$ can be generated by $\lfloor cd/\sqrt{\log{d}}\rfloor$ elements. In this paper, we explicitly estimate $c$
Tracey, Gareth M.
core   +2 more sources

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

On blocks of strongly p-solvable groups [PDF]

, 2006
We prove that a block of a finite strongly p-solvable group G with defect group P is Morita equivalent to its corresponding block of NG(Z(J(P))) via a bimodule with endo-permutation ...
Kessar, R., Linckelmann, M.
core   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Set-partition tableaux and representations of diagram algebras [PDF]

, 2019
The partition algebra is an associative algebra with a basis of set-partition diagrams and multiplication given by diagram concatenation. It contains as subalgebras a large class of diagram algebras including the Brauer, planar partition, rook monoid ...
Halverson, Tom, Jacobson, Theodore N.
core   +3 more sources