Results 41 to 50 of about 1,033,682 (248)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Interdecadal variations, since the middle of the 20th century, in the seasonal cycle of Southern Hemisphere extratropical synoptic scale weather systems, are studied and related to associated anomalies in Southern Australian rainfall over south-west ...
Stacey L. Osbrough +1 more
doaj +1 more source
Universally Balanced Combinatorial Optimization Games
This article surveys studies on universally balanced properties of cooperative games defined in a succinct form. In particular, we focus on combinatorial optimization games in which the values to coalitions are defined through linear optimization ...
Xiaotie Deng, Gabrielle Demange
doaj +1 more source
This study explores the consequences of independent and combined effects of blockings on the northeast Asian cold vortex (NACV), and corresponding cold outbreaks over East Asia (EA) during boreal winters of 1979–2019.
Wenqin Zhuo +4 more
doaj +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The problem is studied by the example of gas condensate fields at the final stage of development, where production wells have abnormally low reservoir pressures and their killing for repair work is a serious challenge requiring a search for new solutions.
R. A. Gasumov, E. R. Gasumov
doaj +1 more source
This paper argues that grammar has a union spell-out principle that dictates that contiguous heads be spelled out by a single morpheme or phrase if there exists a morpheme or phrase in the lexicon with a collection of the features of the contiguous ...
Peter Kinyua Muriungi
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Psychology Data on the Effects of Study Schedules on Category-Member Classification
Subjects ('N' = 100) studied a series of 6 natural exemplars (birds) from each of 12 different categories (families). Birds were presented in one of 4 ways: (1) blocked by category; (2) intermixed; (3) first blocked, then intermixed; or (4) first ...
K. Andrew DeSoto, Cecilia M. Votta
doaj +1 more source

