Results 61 to 70 of about 1,433,685 (263)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

A tight bound on the throughput of queueing networks with blocking [PDF]

open access: yes
In this paper, we present a bounding methodology that allows to compute a tight lower bound on the cycle time of fork--join queueing networks with blocking and with general service time distributions. The methodology relies on two ideas.
SEMAL, Pierre   +2 more
core  

Relationship between the traffic load and the blocking probability.

open access: yes, 2014
Relationship between the traffic load and the blocking probability.
Gwo-Jiun Horng (621132)
core   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

Evaluation of the blocking probability of limited access network

open access: yes, 1994
We derive the probability of a customer finding no available circuit in a limited access network. We analyze a limited access network with a finite number of circuits and several classes of customers.
Ouaily,Montasser
core  

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Blocking probability of large wood and resulting head increase at ogee crest spillways [PDF]

open access: yes, 2019
Large wood increases the hydraulic complexity of rivers, yet it may block and modify the flood discharge capacity of hydraulic structures such as bridges and spillways.
Furlan, Paloma
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Transient blocking probability in a loss system with arbitrary initial conditions [PDF]

open access: yes, 1990
We extend Riordan's work on the transient blocking probability in an M/M/N loss system where he assumes that all servers are initially free. We consider the case when the initial probability distribution is arbitrary and derive an exact expression for ...
Yunus, M.Naim
core   +1 more source

The Gain of Performance of Optical WDM Networks

open access: yesJournal of Computer Systems, Networks, and Communications, 2008
We study the blocking probability and performance of single-fiber and multifiber optical networks with wavelength division multiplexing (WDM). We extend the well-known analytical blocking probability model by Barry and Humblet to the general model, which
Miroslav Bahleda, Karol Blunar
doaj   +1 more source

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